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Small-Molecule Inhibitors of the SOX18 Transcription Factor.
Fontaine F, Overman J, Moustaqil M, Mamidyala S, Salim A, Narasimhan K, Prokoph N, Robertson AAB, Lua L, Alexandrov K, Koopman P, Capon RJ, Sierecki E, Gambin Y, Jauch R, Cooper MA, Zuegg J, Francois M. Fontaine F, et al. Cell Chem Biol. 2017 Mar 16;24(3):346-359. doi: 10.1016/j.chembiol.2017.01.003. Epub 2017 Feb 2. Cell Chem Biol. 2017. PMID: 28163017 Free article.
Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.
Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, Robertson AAB, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, Alexandrov K, Black BL, Hogan BM, De Val S, Capon RJ, Carroll JS, Bailey TL, Koopman P, Jauch R, Cooper MA, Gambin Y, Francois M. Overman J, et al. Among authors: fontaine f. Elife. 2017 Jan 31;6:e21221. doi: 10.7554/eLife.21221. Elife. 2017. PMID: 28137359 Free PMC article.
R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma.
Overman J, Fontaine F, Wylie-Sears J, Moustaqil M, Huang L, Meurer M, Chiang IK, Lesieur E, Patel J, Zuegg J, Pasquier E, Sierecki E, Gambin Y, Hamdan M, Khosrotehrani K, Andelfinger G, Bischoff J, Francois M. Overman J, et al. Among authors: fontaine f. Elife. 2019 Jul 30;8:e43026. doi: 10.7554/eLife.43026. Elife. 2019. PMID: 31358114 Free PMC article.
363 results