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The oncogenic fusion protein DNAJB1-PRKACA can be specifically targeted by peptide-based immunotherapy in fibrolamellar hepatocellular carcinoma.
Bauer J, Köhler N, Maringer Y, Bucher P, Bilich T, Zwick M, Dicks S, Nelde A, Dubbelaar M, Scheid J, Wacker M, Heitmann JS, Schroeder S, Rieth J, Denk M, Richter M, Klein R, Bonzheim I, Luibrand J, Holzer U, Ebinger M, Brecht IB, Bitzer M, Boerries M, Feucht J, Salih HR, Rammensee HG, Hailfinger S, Walz JS. Bauer J, et al. Among authors: feucht j. Nat Commun. 2022 Oct 27;13(1):6401. doi: 10.1038/s41467-022-33746-3. Nat Commun. 2022. PMID: 36302754 Free PMC article.
LINKing signaling domains to enhance CAR T cells.
Bucher P, Feucht J. Bucher P, et al. Among authors: feucht j. Nat Cancer. 2023 Apr;4(4):447-449. doi: 10.1038/s43018-023-00538-7. Nat Cancer. 2023. PMID: 37106112 No abstract available.
[Punt-driver with jaundice - case 1/2014].
Leibold J, Fusco S, Feucht J, Artunc F, Malek N, Bitzer M. Leibold J, et al. Among authors: feucht j. Dtsch Med Wochenschr. 2014 Jan;139(1-2):28. doi: 10.1055/s-0033-1359894. Epub 2014 Jan 3. Dtsch Med Wochenschr. 2014. PMID: 24390847 Free article. German.
Pediatric posttransplant relapsed/refractory B-precursor acute lymphoblastic leukemia shows durable remission by therapy with the T-cell engaging bispecific antibody blinatumomab.
Schlegel P, Lang P, Zugmaier G, Ebinger M, Kreyenberg H, Witte KE, Feucht J, Pfeiffer M, Teltschik HM, Kyzirakos C, Feuchtinger T, Handgretinger R. Schlegel P, et al. Among authors: feucht j. Haematologica. 2014 Jul;99(7):1212-9. doi: 10.3324/haematol.2013.100073. Epub 2014 Apr 11. Haematologica. 2014. PMID: 24727818 Free PMC article.
T-cell responses against CD19+ pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic blasts.
Feucht J, Kayser S, Gorodezki D, Hamieh M, Döring M, Blaeschke F, Schlegel P, Bösmüller H, Quintanilla-Fend L, Ebinger M, Lang P, Handgretinger R, Feuchtinger T. Feucht J, et al. Oncotarget. 2016 Nov 22;7(47):76902-76919. doi: 10.18632/oncotarget.12357. Oncotarget. 2016. PMID: 27708227 Free PMC article.
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy.
Blaeschke F, Paul MC, Schuhmann MU, Rabsteyn A, Schroeder C, Casadei N, Matthes J, Mohr C, Lotfi R, Wagner B, Kaeuferle T, Feucht J, Willier S, Handgretinger R, StevanoviĆ S, Lang P, Feuchtinger T. Blaeschke F, et al. Among authors: feucht j. Cytotherapy. 2019 Sep;21(9):973-986. doi: 10.1016/j.jcyt.2019.06.009. Epub 2019 Jul 25. Cytotherapy. 2019. PMID: 31351799
Efficacy, Safety And Feasibility Of Antiemetic Prophylaxis With Fosaprepitant, Granisetron And Dexamethasone In Pediatric Patients With Hemato-Oncological Malignancies.
Cabanillas Stanchi KM, Ebinger M, Hartmann U, Queudeville M, Feucht J, Ost M, Koch MS, Malaval C, Mezger M, Schober S, Weber S, Michaelis S, Lange V, Lang P, Handgretinger R, Döring M. Cabanillas Stanchi KM, et al. Among authors: feucht j. Drug Des Devel Ther. 2019 Sep 30;13:3439-3451. doi: 10.2147/DDDT.S214264. eCollection 2019. Drug Des Devel Ther. 2019. PMID: 31686784 Free PMC article.
HLA-independent T cell receptors for targeting tumors with low antigen density.
Mansilla-Soto J, Eyquem J, Haubner S, Hamieh M, Feucht J, Paillon N, Zucchetti AE, Li Z, Sjöstrand M, Lindenbergh PL, Saetersmoen M, Dobrin A, Maurin M, Iyer A, Garcia Angus A, Miele MM, Zhao Z, Giavridis T, van der Stegen SJC, Tamzalit F, Rivière I, Huse M, Hendrickson RC, Hivroz C, Sadelain M. Mansilla-Soto J, et al. Among authors: feucht j. Nat Med. 2022 Feb;28(2):345-352. doi: 10.1038/s41591-021-01621-1. Epub 2022 Jan 13. Nat Med. 2022. PMID: 35027758 Free PMC article.
Senolytic CAR T cells reverse senescence-associated pathologies.
Amor C, Feucht J, Leibold J, Ho YJ, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, Peerschke E, Friedman SL, Ponomarev V, Piersigilli A, Sadelain M, Lowe SW. Amor C, et al. Among authors: feucht j. Nature. 2020 Jul;583(7814):127-132. doi: 10.1038/s41586-020-2403-9. Epub 2020 Jun 17. Nature. 2020. PMID: 32555459 Free PMC article.
48 results