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Restoring metabolism of myeloid cells reverses cognitive decline in ageing.
Minhas PS, Latif-Hernandez A, McReynolds MR, Durairaj AS, Wang Q, Rubin A, Joshi AU, He JQ, Gauba E, Liu L, Wang C, Linde M, Sugiura Y, Moon PK, Majeti R, Suematsu M, Mochly-Rosen D, Weissman IL, Longo FM, Rabinowitz JD, Andreasson KI. Minhas PS, et al. Among authors: durairaj as. Nature. 2021 Feb;590(7844):122-128. doi: 10.1038/s41586-020-03160-0. Epub 2021 Jan 20. Nature. 2021. PMID: 33473210 Free PMC article.
TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models.
Wilson EN, Wang C, Swarovski MS, Zera KA, Ennerfelt HE, Wang Q, Chaney A, Gauba E, Ramos Benitez JA, Le Guen Y, Minhas PS, Panchal M, Tan YJ, Blacher E, A Iweka C, Cropper H, Jain P, Liu Q, Mehta SS, Zuckerman AJ, Xin M, Umans J, Huang J, Durairaj AS, Serrano GE, Beach TG, Greicius MD, James ML, Buckwalter MS, McReynolds MR, Rabinowitz JD, Andreasson KI. Wilson EN, et al. Among authors: durairaj as. Nat Neurosci. 2024 May;27(5):873-885. doi: 10.1038/s41593-024-01610-w. Epub 2024 Mar 27. Nat Neurosci. 2024. PMID: 38539014
A mitochondrial inside-out iron-calcium signal reveals drug targets for Parkinson's disease.
Bharat V, Durairaj AS, Vanhauwaert R, Li L, Muir CM, Chandra S, Kwak CS, Le Guen Y, Nandakishore P, Hsieh CH, Rensi SE, Altman RB, Greicius MD, Feng L, Wang X. Bharat V, et al. Among authors: durairaj as. Cell Rep. 2023 Dec 26;42(12):113544. doi: 10.1016/j.celrep.2023.113544. Epub 2023 Dec 6. Cell Rep. 2023. PMID: 38060381 Free PMC article.
Mitochondrial Calcium Transport During Autophagy Initiation.
Chandra S, Katiyar P, Durairaj AS, Wang X. Chandra S, et al. Among authors: durairaj as. Mitochondrial Commun. 2024;2:14-20. doi: 10.1016/j.mitoco.2024.01.002. Epub 2024 Jan 28. Mitochondrial Commun. 2024. PMID: 38347884 Free PMC article.