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Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer.
Di Modugno F, Di Carlo A, Spada S, Palermo B, D'Ambrosio L, D'Andrea D, Morello G, Belmonte B, Sperduti I, Balzano V, Gallo E, Melchionna R, Panetta M, Campo G, De Nicola F, Goeman F, Antoniani B, Carpano S, Frigè G, Warren S, Gallina F, Lambrechts D, Xiong J, Vincent BG, Wheeler N, Bortone DS, Cappuzzo F, Facciolo F, Tripodo C, Visca P, Nisticò P. Di Modugno F, et al. EBioMedicine. 2024 Mar;101:105003. doi: 10.1016/j.ebiom.2024.105003. Epub 2024 Feb 9. EBioMedicine. 2024. PMID: 38340557 Free PMC article.
hMENA isoforms regulate cancer intrinsic type I IFN signaling and extrinsic mechanisms of resistance to immune checkpoint blockade in NSCLC.
Trono P, Tocci A, Palermo B, Di Carlo A, D'Ambrosio L, D'Andrea D, Di Modugno F, De Nicola F, Goeman F, Corleone G, Warren S, Paolini F, Panetta M, Sperduti I, Baldari S, Visca P, Carpano S, Cappuzzo F, Russo V, Tripodo C, Zucali P, Gregorc V, Marchesi F, Nistico P. Trono P, et al. Among authors: di modugno f. J Immunother Cancer. 2023 Aug;11(8):e006913. doi: 10.1136/jitc-2023-006913. J Immunother Cancer. 2023. PMID: 37612043 Free PMC article.
Prognostic impact of alternative splicing-derived hMENA isoforms in resected, node-negative, non-small-cell lung cancer.
Bria E, Di Modugno F, Sperduti I, Iapicca P, Visca P, Alessandrini G, Antoniani B, Pilotto S, Ludovini V, Vannucci J, Bellezza G, Sidoni A, Tortora G, Radisky DC, Crinò L, Cognetti F, Facciolo F, Mottolese M, Milella M, Nisticò P. Bria E, et al. Among authors: di modugno f. Oncotarget. 2014 Nov 30;5(22):11054-63. doi: 10.18632/oncotarget.2609. Oncotarget. 2014. PMID: 25373410 Free PMC article.
The pattern of hMENA isoforms is regulated by TGF-β1 in pancreatic cancer and may predict patient outcome.
Melchionna R, Iapicca P, Di Modugno F, Trono P, Sperduti I, Fassan M, Cataldo I, Rusev BC, Lawlor RT, Diodoro MG, Milella M, Grazi GL, Bissell MJ, Scarpa A, Nisticò P. Melchionna R, et al. Among authors: di modugno f. Oncoimmunology. 2016 Aug 12;5(12):e1221556. doi: 10.1080/2162402X.2016.1221556. eCollection 2016. Oncoimmunology. 2016. PMID: 28123868 Free PMC article.
hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis.
Di Modugno F, Spada S, Palermo B, Visca P, Iapicca P, Di Carlo A, Antoniani B, Sperduti I, Di Benedetto A, Terrenato I, Mottolese M, Gandolfi F, Facciolo F, Chen EI, Schwartz MA, Santoni A, Bissell MJ, Nisticò P. Di Modugno F, et al. Among authors: di benedetto a, di carlo a. Oncogene. 2018 Oct;37(42):5605-5617. doi: 10.1038/s41388-018-0364-3. Epub 2018 Jun 15. Oncogene. 2018. PMID: 29907768 Free PMC article.
The actin modulator hMENA regulates GAS6-AXL axis and pro-tumor cancer/stromal cell cooperation.
Melchionna R, Spada S, Di Modugno F, D'Andrea D, Di Carlo A, Panetta M, Mileo AM, Sperduti I, Antoniani B, Gallo E, Lawlor RT, Piemonti L, Visca P, Milella M, Grazi GL, Facciolo F, Chen E, Scarpa A, Nisticò P. Melchionna R, et al. Among authors: di modugno f. EMBO Rep. 2020 Nov 5;21(11):e50078. doi: 10.15252/embr.202050078. Epub 2020 Sep 10. EMBO Rep. 2020. PMID: 32909687 Free PMC article.
hMENA(11a), a hMENA isoform sending survival signals.
Trono P, Di Modugno F, Nisticò P. Trono P, et al. Among authors: di modugno f. Mol Cell Oncol. 2015 Aug 27;3(2):e1083648. doi: 10.1080/23723556.2015.1083648. eCollection 2016 Mar. Mol Cell Oncol. 2015. PMID: 27308605 Free PMC article.
Transcription factors in fibroblast plasticity and CAF heterogeneity.
Melchionna R, Trono P, Di Carlo A, Di Modugno F, Nisticò P. Melchionna R, et al. Among authors: di modugno f. J Exp Clin Cancer Res. 2023 Dec 20;42(1):347. doi: 10.1186/s13046-023-02934-4. J Exp Clin Cancer Res. 2023. PMID: 38124183 Free PMC article. Review.
45 results