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A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1.
Numata M, Haginoya N, Shiroishi M, Hirata T, Sato-Otsubo A, Yoshikawa K, Takata Y, Nagase R, Kashimoto Y, Suzuki M, Schulte N, Polier G, Kurimoto A, Tomoe Y, Toyota A, Yoneyama T, Imai E, Watanabe K, Hamada T, Kanada R, Watanabe J, Kagoshima Y, Tokumaru E, Murata K, Baba T, Shinozaki T, Ohtsuka M, Goto K, Karibe T, Deguchi T, Gocho Y, Yoshida M, Tomizawa D, Kato M, Tsutsumi S, Kitagawa M, Abe Y. Numata M, et al. Among authors: deguchi t. Cancer Cell Int. 2023 Feb 25;23(1):36. doi: 10.1186/s12935-023-02877-y. Cancer Cell Int. 2023. PMID: 36841758 Free PMC article.
Multiplex fusion gene testing in pediatric acute myeloid leukemia.
Iijima-Yamashita Y, Matsuo H, Yamada M, Deguchi T, Kiyokawa N, Shimada A, Tawa A, Takahashi H, Tomizawa D, Taga T, Kinoshita A, Adachi S, Horibe K. Iijima-Yamashita Y, et al. Among authors: deguchi t. Pediatr Int. 2018 Jan;60(1):47-51. doi: 10.1111/ped.13451. Pediatr Int. 2018. PMID: 29105243
Comparison of clonazepam and levetiracetam in children for prevention of busulfan-induced seizure in hematopoietic stem cell transplantation.
Tsujimoto SI, Shirai R, Utano T, Osumi T, Matsumoto K, Shioda Y, Kiyotani C, Uchiyama T, Deguchi T, Terashima K, Tomizawa D, Matsumoto K, Kato M. Tsujimoto SI, et al. Among authors: deguchi t. Int J Hematol. 2020 Mar;111(3):463-466. doi: 10.1007/s12185-019-02795-8. Epub 2019 Dec 20. Int J Hematol. 2020. PMID: 31863341
Successful Umbilical Cord Blood Transplantation With Reduced-intensity Conditioning for Acute Myeloid Leukemia in a Child With Shwachman-Diamond Syndrome.
Yoshimura S, Mizuno T, Osumi T, Shioda Y, Kiyotani C, Terashima K, Deguchi T, Nakadate H, Kato M, Matsumoto K, Tomizawa D. Yoshimura S, et al. Among authors: deguchi t. J Pediatr Hematol Oncol. 2021 Apr 1;43(3):e414-e418. doi: 10.1097/MPH.0000000000001773. J Pediatr Hematol Oncol. 2021. PMID: 32134838
High prevalence of SMARCB1 constitutional abnormalities including mosaicism in malignant rhabdoid tumors.
Shirai R, Osumi T, Terashima K, Kiyotani C, Uchiyama M, Tsujimoto S, Yoshida M, Yoshida K, Uchiyama T, Tomizawa D, Shioda Y, Sekiguchi M, Watanabe K, Keino D, Ueno-Yokohata H, Ohki K, Takita J, Ito S, Deguchi T, Kiyokawa N, Ogiwara H, Hishiki T, Ogawa S, Okita H, Matsumoto K, Yoshioka T, Kato M. Shirai R, et al. Among authors: deguchi t. Eur J Hum Genet. 2020 Aug;28(8):1124-1128. doi: 10.1038/s41431-020-0614-z. Epub 2020 Mar 26. Eur J Hum Genet. 2020. PMID: 32218533 Free PMC article.
Living-donor liver transplantation providing an adequate chemotherapy for a pediatric patient with anaplastic large cell lymphoma complicated with liver failure due to the aggravation of biliary hepatopathy by secondary hemophagocytic lymphohistiocytosis.
Sakamoto K, Osumi T, Yoshimura S, Shimizu S, Kato M, Tomizawa D, Fukuda A, Sakamoto S, Nakano N, Yoshioka T, Miyazaki O, Nosaka S, Deguchi T, Kiyokawa N, Kasahara M, Matsumoto K. Sakamoto K, et al. Among authors: deguchi t. Int J Hematol. 2020 Dec;112(6):900-905. doi: 10.1007/s12185-020-02949-z. Epub 2020 Jul 24. Int J Hematol. 2020. PMID: 32710432
Prevalence of germline GATA2 and SAMD9/9L variants in paediatric haematological disorders with monosomy 7.
Yoshida M, Tanase-Nakao K, Shima H, Shirai R, Yoshida K, Osumi T, Deguchi T, Mori M, Arakawa Y, Takagi M, Miyamura T, Sakaguchi K, Toyoda H, Ishida H, Sakata N, Imamura T, Kawahara Y, Morimoto A, Koike T, Yagasaki H, Ito S, Tomizawa D, Kiyokawa N, Narumi S, Kato M. Yoshida M, et al. Among authors: deguchi t. Br J Haematol. 2020 Dec;191(5):835-843. doi: 10.1111/bjh.17006. Epub 2020 Aug 7. Br J Haematol. 2020. PMID: 32770553 Free article. Clinical Trial.
Genetic features of precursor B-cell phenotype Burkitt leukemia with IGH-MYC rearrangement.
Yoshida M, Tomizawa D, Yoshimura S, Osumi T, Nakabayashi K, Ogata-Kawata H, Ishiwata K, Sato-Otsubo A, Kimura Y, Ito S, Matsumoto K, Deguchi T, Kiyokawa N, Yoshioka T, Hata K, Kato M. Yoshida M, et al. Among authors: deguchi t. Cancer Rep (Hoboken). 2022 Jul;5(7):e1545. doi: 10.1002/cnr2.1545. Epub 2021 Sep 2. Cancer Rep (Hoboken). 2022. PMID: 34472720 Free PMC article.
Hematopoietic stem cell transplantation for infants with high-risk KMT2A gene-rearranged acute lymphoblastic leukemia.
Takachi T, Watanabe T, Miyamura T, Moriya Saito A, Deguchi T, Hori T, Yamada T, Ohmori S, Haba M, Aoki Y, Ishimaru S, Sasaki S, Ohshima J, Iguchi A, Takahashi Y, Hyakuna N, Manabe A, Horibe K, Ishii E, Koh K, Tomizawa D. Takachi T, et al. Among authors: deguchi t. Blood Adv. 2021 Oct 12;5(19):3891-3899. doi: 10.1182/bloodadvances.2020004157. Blood Adv. 2021. PMID: 34500465 Free PMC article.
1,090 results