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Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS-MAPK Pathway Inhibition in Pancreatic Cancer.
Ravichandran M, Hu J, Cai C, Ward NP, Venida A, Foakes C, Kuljanin M, Yang A, Hennessey CJ, Yang Y, Desousa BR, Rademaker G, Staes AAL, Cakir Z, Jain IH, Aguirre AJ, Mancias JD, Shen Y, DeNicola GM, Perera RM. Ravichandran M, et al. Among authors: denicola gm. Cancer Discov. 2022 Sep 2;12(9):2198-2219. doi: 10.1158/2159-8290.CD-22-0044. Cancer Discov. 2022. PMID: 35771494 Free PMC article.
C-Raf is required for the initiation of lung cancer by K-Ras(G12D).
Karreth FA, Frese KK, DeNicola GM, Baccarini M, Tuveson DA. Karreth FA, et al. Among authors: denicola gm. Cancer Discov. 2011 Jul;1(2):128-36. doi: 10.1158/2159-8290.CD-10-0044. Epub 2011 May 11. Cancer Discov. 2011. PMID: 22043453 Free PMC article.
Stressing Out PanIN: NRF2 Pushes over the Edge.
Torrente L, DeNicola GM. Torrente L, et al. Among authors: denicola gm. Cancer Cell. 2017 Dec 11;32(6):723-725. doi: 10.1016/j.ccell.2017.11.014. Cancer Cell. 2017. PMID: 29232549 Free article.
Oncogenic KRAS Induces NIX-Mediated Mitophagy to Promote Pancreatic Cancer.
Humpton TJ, Alagesan B, DeNicola GM, Lu D, Yordanov GN, Leonhardt CS, Yao MA, Alagesan P, Zaatari MN, Park Y, Skepper JN, Macleod KF, Perez-Mancera PA, Murphy MP, Evan GI, Vousden KH, Tuveson DA. Humpton TJ, et al. Among authors: denicola gm. Cancer Discov. 2019 Sep;9(9):1268-1287. doi: 10.1158/2159-8290.CD-18-1409. Epub 2019 Jul 1. Cancer Discov. 2019. PMID: 31263025 Free PMC article.
Sulfur metabolism and its contribution to malignancy.
Ward NP, DeNicola GM. Ward NP, et al. Among authors: denicola gm. Int Rev Cell Mol Biol. 2019;347:39-103. doi: 10.1016/bs.ircmb.2019.05.001. Epub 2019 Jun 17. Int Rev Cell Mol Biol. 2019. PMID: 31451216 Review.
The Golgi: Keeping It Unapologetically Basic.
Ward NP, DeNicola GM. Ward NP, et al. Among authors: denicola gm. Cancer Discov. 2020 Jun;10(6):768-770. doi: 10.1158/2159-8290.CD-20-0357. Cancer Discov. 2020. PMID: 32482665
GSH hoards all the cysteine-what a slimy thing to do.
Ward NP, DeNicola GM. Ward NP, et al. Among authors: denicola gm. Nat Metab. 2021 Mar;3(3):297-298. doi: 10.1038/s42255-021-00365-z. Nat Metab. 2021. PMID: 33664498 No abstract available.
IL1RAP Pulls a Double Shift in the Cysteine Factory.
Yoon SJ, DeNicola GM. Yoon SJ, et al. Among authors: denicola gm. Cancer Discov. 2021 Nov;11(11):2679-2681. doi: 10.1158/2159-8290.CD-21-1053. Cancer Discov. 2021. PMID: 34725089
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