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Accurate de novo design of membrane-traversing macrocycles.
Bhardwaj G, O'Connor J, Rettie S, Huang YH, Ramelot TA, Mulligan VK, Alpkilic GG, Palmer J, Bera AK, Bick MJ, Di Piazza M, Li X, Hosseinzadeh P, Craven TW, Tejero R, Lauko A, Choi R, Glynn C, Dong L, Griffin R, van Voorhis WC, Rodriguez J, Stewart L, Montelione GT, Craik D, Baker D. Bhardwaj G, et al. Among authors: craik d. Cell. 2022 Sep 15;185(19):3520-3532.e26. doi: 10.1016/j.cell.2022.07.019. Epub 2022 Aug 29. Cell. 2022. PMID: 36041435 Free PMC article.
Cyclotide interactions with the nematode external surface.
Colgrave ML, Huang YH, Craik DJ, Kotze AC. Colgrave ML, et al. Antimicrob Agents Chemother. 2010 May;54(5):2160-6. doi: 10.1128/AAC.01306-09. Epub 2010 Mar 8. Antimicrob Agents Chemother. 2010. PMID: 20211894 Free PMC article.
Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities.
Henriques ST, Huang YH, Rosengren KJ, Franquelim HG, Carvalho FA, Johnson A, Sonza S, Tachedjian G, Castanho MA, Daly NL, Craik DJ. Henriques ST, et al. J Biol Chem. 2011 Jul 8;286(27):24231-41. doi: 10.1074/jbc.M111.253393. Epub 2011 May 16. J Biol Chem. 2011. PMID: 21576247 Free PMC article.
885 results