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Fucosyltransferase-specific inhibition via next generation of fucose mimetics.
Martin KC, Tricomi J, Corzana F, García-García A, Ceballos-Laita L, Hicks T, Monaco S, Angulo J, Hurtado-Guerrero R, Richichi B, Sackstein R. Martin KC, et al. Among authors: corzana f. Chem Commun (Camb). 2021 Jan 28;57(9):1145-1148. doi: 10.1039/d0cc04847j. Epub 2021 Jan 7. Chem Commun (Camb). 2021. PMID: 33411866
Rational design of a Tn antigen mimic.
Corzana F, Busto JH, Marcelo F, de Luis MG, Asensio JL, Martín-Santamaría S, Sáenz Y, Torres C, Jiménez-Barbero J, Avenoza A, Peregrina JM. Corzana F, et al. Chem Commun (Camb). 2011 May 14;47(18):5319-21. doi: 10.1039/c1cc10192g. Epub 2011 Mar 31. Chem Commun (Camb). 2011. PMID: 21451866 Free article.
Substrate-guided front-face reaction revealed by combined structural snapshots and metadynamics for the polypeptide N-acetylgalactosaminyltransferase 2.
Lira-Navarrete E, Iglesias-Fernández J, Zandberg WF, Compañón I, Kong Y, Corzana F, Pinto BM, Clausen H, Peregrina JM, Vocadlo DJ, Rovira C, Hurtado-Guerrero R. Lira-Navarrete E, et al. Among authors: corzana f. Angew Chem Int Ed Engl. 2014 Jul 28;53(31):8206-10. doi: 10.1002/anie.201402781. Epub 2014 Jun 20. Angew Chem Int Ed Engl. 2014. PMID: 24954443
Serine versus threonine glycosylation with α-O-GalNAc: unexpected selectivity in their molecular recognition with lectins.
Madariaga D, Martínez-Sáez N, Somovilla VJ, García-García L, Berbis MÁ, Valero-Gónzalez J, Martín-Santamaría S, Hurtado-Guerrero R, Asensio JL, Jiménez-Barbero J, Avenoza A, Busto JH, Corzana F, Peregrina JM. Madariaga D, et al. Among authors: corzana f. Chemistry. 2014 Sep 22;20(39):12616-27. doi: 10.1002/chem.201403700. Epub 2014 Aug 8. Chemistry. 2014. PMID: 25111627
Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition.
Madariaga D, Martínez-Sáez N, Somovilla VJ, Coelho H, Valero-González J, Castro-López J, Asensio JL, Jiménez-Barbero J, Busto JH, Avenoza A, Marcelo F, Hurtado-Guerrero R, Corzana F, Peregrina JM. Madariaga D, et al. Among authors: corzana f. ACS Chem Biol. 2015 Mar 20;10(3):747-56. doi: 10.1021/cb500855x. Epub 2014 Dec 10. ACS Chem Biol. 2015. PMID: 25457745
Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation.
Lira-Navarrete E, de Las Rivas M, Compañón I, Pallarés MC, Kong Y, Iglesias-Fernández J, Bernardes GJ, Peregrina JM, Rovira C, Bernadó P, Bruscolini P, Clausen H, Lostao A, Corzana F, Hurtado-Guerrero R. Lira-Navarrete E, et al. Among authors: corzana f. Nat Commun. 2015 May 5;6:6937. doi: 10.1038/ncomms7937. Nat Commun. 2015. PMID: 25939779 Free PMC article.
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody.
Martínez-Sáez N, Castro-López J, Valero-González J, Madariaga D, Compañón I, Somovilla VJ, Salvadó M, Asensio JL, Jiménez-Barbero J, Avenoza A, Busto JH, Bernardes GJ, Peregrina JM, Hurtado-Guerrero R, Corzana F. Martínez-Sáez N, et al. Among authors: corzana f. Angew Chem Int Ed Engl. 2015 Aug 17;54(34):9830-4. doi: 10.1002/anie.201502813. Epub 2015 Jun 26. Angew Chem Int Ed Engl. 2015. PMID: 26118689 Free PMC article.
A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2.
Valero-González J, Leonhard-Melief C, Lira-Navarrete E, Jiménez-Osés G, Hernández-Ruiz C, Pallarés MC, Yruela I, Vasudevan D, Lostao A, Corzana F, Takeuchi H, Haltiwanger RS, Hurtado-Guerrero R. Valero-González J, et al. Among authors: corzana f. Nat Chem Biol. 2016 Apr;12(4):240-6. doi: 10.1038/nchembio.2019. Epub 2016 Feb 8. Nat Chem Biol. 2016. PMID: 26854667 Free PMC article.
146 results