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Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody.
Macías-León J , Bermejo IA , Asín A , García-García A , Compañón I , Jiménez-Moreno E , Coelho H , Mangini V , Albuquerque IS , Marcelo F , Asensio JL , Bernardes GJL , Joshi HJ , Fiammengo R , Blixt O , Hurtado-Guerrero R , Corzana F . Macías-León J , et al. Among authors: coelho h. Chem Commun (Camb). 2020 Dec 8;56(96):15137-15140. doi: 10.1039/d0cc06349e. Chem Commun (Camb). 2020. PMID: 33211039
Delineating binding modes of Gal/GalNAc and structural elements of the molecular recognition of tumor-associated mucin glycopeptides by the human macrophage galactose-type lectin.
Marcelo F, Garcia-Martin F, Matsushita T, Sardinha J, Coelho H, Oude-Vrielink A, Koller C, André S, Cabrita EJ, Gabius HJ, Nishimura S, Jiménez-Barbero J, Cañada FJ. Marcelo F, et al. Among authors: coelho h. Chemistry. 2014 Dec 1;20(49):16147-55. doi: 10.1002/chem.201404566. Epub 2014 Oct 16. Chemistry. 2014. PMID: 25324212
Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition.
Madariaga D, Martínez-Sáez N, Somovilla VJ, Coelho H, Valero-González J, Castro-López J, Asensio JL, Jiménez-Barbero J, Busto JH, Avenoza A, Marcelo F, Hurtado-Guerrero R, Corzana F, Peregrina JM. Madariaga D, et al. Among authors: coelho h. ACS Chem Biol. 2015 Mar 20;10(3):747-56. doi: 10.1021/cb500855x. Epub 2014 Dec 10. ACS Chem Biol. 2015. PMID: 25457745
The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.
Coelho H, Matsushita T, Artigas G, Hinou H, Cañada FJ, Lo-Man R, Leclerc C, Cabrita EJ, Jiménez-Barbero J, Nishimura S, Garcia-Martín F, Marcelo F. Coelho H, et al. J Am Chem Soc. 2015 Oct 7;137(39):12438-41. doi: 10.1021/jacs.5b06787. Epub 2015 Sep 22. J Am Chem Soc. 2015. PMID: 26366611
The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences.
de Las Rivas M, Lira-Navarrete E, Daniel EJP, Compañón I, Coelho H, Diniz A, Jiménez-Barbero J, Peregrina JM, Clausen H, Corzana F, Marcelo F, Jiménez-Osés G, Gerken TA, Hurtado-Guerrero R. de Las Rivas M, et al. Among authors: coelho h. Nat Commun. 2017 Dec 5;8(1):1959. doi: 10.1038/s41467-017-02006-0. Nat Commun. 2017. PMID: 29208955 Free PMC article.
Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4.
de Las Rivas M, Paul Daniel EJ, Coelho H, Lira-Navarrete E, Raich L, Compañón I, Diniz A, Lagartera L, Jiménez-Barbero J, Clausen H, Rovira C, Marcelo F, Corzana F, Gerken TA, Hurtado-Guerrero R. de Las Rivas M, et al. Among authors: coelho h. ACS Cent Sci. 2018 Sep 26;4(9):1274-1290. doi: 10.1021/acscentsci.8b00488. Epub 2018 Sep 14. ACS Cent Sci. 2018. PMID: 30276263 Free PMC article.
Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3.
de Las Rivas M, Paul Daniel EJ, Narimatsu Y, Compañón I, Kato K, Hermosilla P, Thureau A, Ceballos-Laita L, Coelho H, Bernadó P, Marcelo F, Hansen L, Maeda R, Lostao A, Corzana F, Clausen H, Gerken TA, Hurtado-Guerrero R. de Las Rivas M, et al. Among authors: coelho h. Nat Chem Biol. 2020 Mar;16(3):351-360. doi: 10.1038/s41589-019-0444-x. Epub 2020 Jan 13. Nat Chem Biol. 2020. PMID: 31932717 Free PMC article.
330 results