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Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy.
Chen YJ, Li GN, Li XJ, Wei LX, Fu MJ, Cheng ZL, Yang Z, Zhu GQ, Wang XD, Zhang C, Zhang JY, Sun YP, Saiyin H, Zhang J, Liu WR, Zhu WW, Guan KL, Xiong Y, Yang Y, Ye D, Chen LL. Chen YJ, et al. Among authors: chen ll. Sci Adv. 2023 Apr 28;9(17):eadg0654. doi: 10.1126/sciadv.adg0654. Epub 2023 Apr 28. Sci Adv. 2023. PMID: 37115931 Free PMC article.
SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer.
Chen XF, Tian MX, Sun RQ, Zhang ML, Zhou LS, Jin L, Chen LL, Zhou WJ, Duan KL, Chen YJ, Gao C, Cheng ZL, Wang F, Zhang JY, Sun YP, Yu HX, Zhao YZ, Yang Y, Liu WR, Shi YH, Xiong Y, Guan KL, Ye D. Chen XF, et al. Among authors: chen ll, chen yj. EMBO Rep. 2018 May;19(5):e45124. doi: 10.15252/embr.201745124. Epub 2018 Feb 28. EMBO Rep. 2018. PMID: 29491006 Free PMC article.
Tumor suppressor CEBPA interacts with and inhibits DNMT3A activity.
Chen X, Zhou W, Song RH, Liu S, Wang S, Chen Y, Gao C, He C, Xiao J, Zhang L, Wang T, Liu P, Duan K, Cheng Z, Zhang C, Zhang J, Sun Y, Jackson F, Lan F, Liu Y, Xu Y, Wong JJ, Wang P, Yang H, Xiong Y, Chen T, Li Y, Ye D. Chen X, et al. Sci Adv. 2022 Jan 28;8(4):eabl5220. doi: 10.1126/sciadv.abl5220. Epub 2022 Jan 26. Sci Adv. 2022. PMID: 35080973 Free PMC article.
The pattern of tumor progression on first-line immune checkpoint inhibitor-based systemic therapy for Chinese advanced hepatocellular carcinoma -CLEAP 004 study.
Yang CX, Pan YX, Ye F, Zhu XD, Xue J, Li X, Yuan ZG, Zhang L, Xu L, Chen YJ, Wang NY, Sun HC, Liu XF; China Liver Cancer Study Group Young Investigators (CLEAP). Yang CX, et al. Among authors: chen yj. Front Immunol. 2024 Apr 22;15:1310239. doi: 10.3389/fimmu.2024.1310239. eCollection 2024. Front Immunol. 2024. PMID: 38711515 Free PMC article.
5,289 results