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Human acyl-coenzyme A:cholesterol acyltransferase 1 (acat1) sequences located in two different chromosomes (7 and 1) are required to produce a novel ACAT1 isoenzyme with additional sequence at the N terminus.
Yang L, Lee O, Chen J, Chen J, Chang CC, Zhou P, Wang ZZ, Ma HH, Sha HF, Feng JX, Wang Y, Yang XY, Wang L, Dong R, Ornvold K, Li BL, Chang TY. Yang L, et al. Among authors: chen j. J Biol Chem. 2004 Oct 29;279(44):46253-62. doi: 10.1074/jbc.M408155200. Epub 2004 Aug 18. J Biol Chem. 2004. PMID: 15319423 Free article.
APOBEC3 induces mutations during repair of CRISPR-Cas9-generated DNA breaks.
Lei L, Chen H, Xue W, Yang B, Hu B, Wei J, Wang L, Cui Y, Li W, Wang J, Yan L, Shang W, Gao J, Sha J, Zhuang M, Huang X, Shen B, Yang L, Chen J. Lei L, et al. Among authors: chen j, chen h. Nat Struct Mol Biol. 2018 Jan;25(1):45-52. doi: 10.1038/s41594-017-0004-6. Epub 2017 Dec 11. Nat Struct Mol Biol. 2018. PMID: 29323274
Base editing with a Cpf1-cytidine deaminase fusion.
Li X, Wang Y, Liu Y, Yang B, Wang X, Wei J, Lu Z, Zhang Y, Wu J, Huang X, Yang L, Chen J. Li X, et al. Among authors: chen j. Nat Biotechnol. 2018 Apr;36(4):324-327. doi: 10.1038/nbt.4102. Epub 2018 Mar 19. Nat Biotechnol. 2018. PMID: 29553573
Development and Application of Base Editors.
Yang B, Yang L, Chen J. Yang B, et al. Among authors: chen j. CRISPR J. 2019 Apr;2(2):91-104. doi: 10.1089/crispr.2019.0001. CRISPR J. 2019. PMID: 30998092 Review.
To BE or not to BE, that is the question.
Chen J, Yang B, Yang L. Chen J, et al. Nat Biotechnol. 2019 May;37(5):520-522. doi: 10.1038/s41587-019-0119-x. Nat Biotechnol. 2019. PMID: 31000812 No abstract available.
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