Chalk R - Search Results

1

Structural Insights into Notum Covalent Inhibition.

Zhao Y, Svensson F, Steadman D, Frew S, Monaghan A, Bictash M, Moreira T, Chalk R, Lu W, Fish PV, Jones EY. Zhao Y, et al. Among authors: chalk r. J Med Chem. 2021 Aug 12;64(15):11354-11363. doi: 10.1021/acs.jmedchem.1c00701. Epub 2021 Jul 22. J Med Chem. 2021. PMID: 34292747 Free PMC article.

2

Identification, mapping and relative quantitation of SARS-CoV-2 Spike glycopeptides by Mass-Retention Time Fingerprinting.

Chalk R, Greenland WEP, Moreira T, Coker J, Mukhopadhyay SMM, Williams E, Manning C, Bohstedt T, McCrorie R, Fernandez-Cid A, Burgess-Brown NA. Chalk R, et al. Commun Biol. 2021 Aug 3;4(1):934. doi: 10.1038/s42003-021-02455-w. Commun Biol. 2021. PMID: 34345007 Free PMC article.

3

Structural Insights into the MMACHC-MMADHC Protein Complex Involved in Vitamin B12 Trafficking.

Froese DS, Kopec J, Fitzpatrick F, Schuller M, McCorvie TJ, Chalk R, Plessl T, Fettelschoss V, Fowler B, Baumgartner MR, Yue WW. Froese DS, et al. Among authors: chalk r. J Biol Chem. 2015 Dec 4;290(49):29167-77. doi: 10.1074/jbc.M115.683268. Epub 2015 Oct 19. J Biol Chem. 2015. PMID: 26483544 Free PMC article.

4

Structural characterization of human urea transporters UT-A and UT-B and their inhibition.

Chi G, Dietz L, Tang H, Snee M, Scacioc A, Wang D, Mckinley G, Mukhopadhyay SMM, Pike ACW, Chalk R, Burgess-Brown NA, Timmermans JP, van Putte W, Robinson CV, Dürr KL. Chi G, et al. Among authors: chalk r. Sci Adv. 2023 Sep 29;9(39):eadg8229. doi: 10.1126/sciadv.adg8229. Epub 2023 Sep 29. Sci Adv. 2023. PMID: 37774028 Free PMC article.

5

Tricyclic cell-penetrating peptides for efficient delivery of functional antibodies into cancer cells.

Tietz O, Cortezon-Tamarit F, Chalk R, Able S, Vallis KA. Tietz O, et al. Among authors: chalk r. Nat Chem. 2022 Mar;14(3):284-293. doi: 10.1038/s41557-021-00866-0. Epub 2022 Feb 10. Nat Chem. 2022. PMID: 35145246

6

Molecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase.

McCorvie TJ, Kopec J, Pey AL, Fitzpatrick F, Patel D, Chalk R, Shrestha L, Yue WW. McCorvie TJ, et al. Among authors: chalk r. Hum Mol Genet. 2016 Jun 1;25(11):2234-2244. doi: 10.1093/hmg/ddw091. Epub 2016 Mar 22. Hum Mol Genet. 2016. PMID: 27005423 Free PMC article.

7

Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition.

Froese DS, Kopec J, Rembeza E, Bezerra GA, Oberholzer AE, Suormala T, Lutz S, Chalk R, Borkowska O, Baumgartner MR, Yue WW. Froese DS, et al. Among authors: chalk r. Nat Commun. 2018 Jun 11;9(1):2261. doi: 10.1038/s41467-018-04735-2. Nat Commun. 2018. PMID: 29891918 Free PMC article.

8

High-performance liquid chromatography separation and intact mass analysis of detergent-solubilized integral membrane proteins.

Berridge G, Chalk R, D'Avanzo N, Dong L, Doyle D, Kim JI, Xia X, Burgess-Brown N, Deriso A, Carpenter EP, Gileadi O. Berridge G, et al. Among authors: chalk r. Anal Biochem. 2011 Mar 15;410(2):272-80. doi: 10.1016/j.ab.2010.11.008. Epub 2010 Nov 17. Anal Biochem. 2011. PMID: 21093405 Free PMC article.

9

Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).

Grieben M, Pike AC, Shintre CA, Venturi E, El-Ajouz S, Tessitore A, Shrestha L, Mukhopadhyay S, Mahajan P, Chalk R, Burgess-Brown NA, Sitsapesan R, Huiskonen JT, Carpenter EP. Grieben M, et al. Among authors: chalk r. Nat Struct Mol Biol. 2017 Feb;24(2):114-122. doi: 10.1038/nsmb.3343. Epub 2016 Dec 19. Nat Struct Mol Biol. 2017. PMID: 27991905

10

Mass Spectrometric Analysis of Proteins.

Chalk R. Chalk R. Methods Mol Biol. 2017;1586:373-395. doi: 10.1007/978-1-4939-6887-9_25. Methods Mol Biol. 2017. PMID: 28470619

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