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A2B adenosine receptor antagonists: recent developments.
Cacciari B, Pastorin G, Bolcato C, Spalluto G, Bacilieri M, Moro S. Cacciari B, et al. Mini Rev Med Chem. 2005 Dec;5(12):1053-60. doi: 10.2174/138955705774933374. Mini Rev Med Chem. 2005. PMID: 16375751 Review.
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation.
Pastorin G, Da Ros T, Spalluto G, Deflorian F, Moro S, Cacciari B, Baraldi PG, Gessi S, Varani K, Borea PA. Pastorin G, et al. Among authors: cacciari b. J Med Chem. 2003 Sep 25;46(20):4287-96. doi: 10.1021/jm030852k. J Med Chem. 2003. PMID: 13678407
Combined target-based and ligand-based drug design approach as a tool to define a novel 3D-pharmacophore model of human A3 adenosine receptor antagonists: pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives as a key study.
Moro S, Braiuca P, Deflorian F, Ferrari C, Pastorin G, Cacciari B, Baraldi PG, Varani K, Borea PA, Spalluto G. Moro S, et al. Among authors: cacciari b. J Med Chem. 2005 Jan 13;48(1):152-62. doi: 10.1021/jm049662f. J Med Chem. 2005. PMID: 15634009
Synthesis and biological studies of a new series of 5-heteroarylcarbamoylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as human A3 adenosine receptor antagonists. Influence of the heteroaryl substituent on binding affinity and molecular modeling investigations.
Pastorin G, Da Ros T, Bolcato C, Montopoli C, Moro S, Cacciari B, Baraldi PG, Varani K, Borea PA, Spalluto G. Pastorin G, et al. Among authors: cacciari b. J Med Chem. 2006 Mar 9;49(5):1720-9. doi: 10.1021/jm051147+. J Med Chem. 2006. PMID: 16509587
79 results