Abstract
There are pharmacological evidences that A(2B) receptors are involved in inflammatory processes, such as asthma. For this reason, many efforts has been made for identifying selective A(2B) antagonists as anti-asthmatic agents. The updated material related to this field has been rationalised and arranged in order to offer an overview of the topic.
MeSH terms
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Adenosine A2 Receptor Antagonists*
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Amino Acid Sequence
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Animals
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Anti-Asthmatic Agents / pharmacology*
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Anti-Asthmatic Agents / therapeutic use
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Anti-Inflammatory Agents / pharmacology*
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Anti-Inflammatory Agents / therapeutic use
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Asthma / drug therapy
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Asthma / pathology
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Binding Sites
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Drug Design
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Humans
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Molecular Sequence Data
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Quinazolines / chemistry
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Quinazolines / metabolism
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Triazoles / chemistry
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Triazoles / metabolism
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Xanthines / chemistry
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Xanthines / metabolism
Substances
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Adenosine A2 Receptor Antagonists
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Anti-Asthmatic Agents
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Anti-Inflammatory Agents
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Quinazolines
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Triazoles
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Xanthines