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The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.
Manry J, Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Mégarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs CM, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY, Shcherbina A, Lau… See abstract for full author list ➔ Manry J, et al. Among authors: burrel s. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2200413119. doi: 10.1073/pnas.2200413119. Epub 2022 May 16. Proc Natl Acad Sci U S A. 2022. PMID: 35576468 Free PMC article.
Medical features of COVID-19 and influenza infection: A comparative study in Paris, France.
Faury H, Courboulès C, Payen M, Jary A, Hausfater P, Luyt C, Dres M, Pourcher V, Abdi B, Wirden M, Calvez V, Marcelin AG, Boutolleau D, Burrel S. Faury H, et al. Among authors: burrel s. J Infect. 2021 Feb;82(2):e36-e39. doi: 10.1016/j.jinf.2020.08.017. Epub 2020 Aug 14. J Infect. 2021. PMID: 32798533 Free PMC article. No abstract available.
Ventilator-associated pneumonia in patients with SARS-CoV-2-associated acute respiratory distress syndrome requiring ECMO: a retrospective cohort study.
Luyt CE, Sahnoun T, Gautier M, Vidal P, Burrel S, Pineton de Chambrun M, Chommeloux J, Desnos C, Arzoine J, Nieszkowska A, Bréchot N, Schmidt M, Hekimian G, Boutolleau D, Robert J, Combes A, Chastre J. Luyt CE, et al. Among authors: burrel s. Ann Intensive Care. 2020 Nov 23;10(1):158. doi: 10.1186/s13613-020-00775-4. Ann Intensive Care. 2020. PMID: 33230710 Free PMC article.
Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers.
Marot S, Malet I, Leducq V, Zafilaza K, Sterlin D, Planas D, Gothland A, Jary A, Dorgham K, Bruel T; Sorbonne Université SARS-CoV-2 Neutralizing Antibodies Study Group; Burrel S, Boutolleau D, Schwartz O, Gorochov G, Calvez V, Marcelin AG. Marot S, et al. Among authors: burrel s. Nat Commun. 2021 Feb 8;12(1):844. doi: 10.1038/s41467-021-21111-9. Nat Commun. 2021. PMID: 33558507 Free PMC article.
Plasma Exchange to Rescue Patients with Autoantibodies Against Type I Interferons and Life-Threatening COVID-19 Pneumonia.
de Prost N, Bastard P, Arrestier R, Fourati S, Mahévas M, Burrel S, Dorgham K, Gorochov G, Tandjaoui-Lambiotte Y, Azzaoui I, Fernandes I, Combes A, Casanova JL, Mekontso-Dessap A, Luyt CE. de Prost N, et al. Among authors: burrel s. J Clin Immunol. 2021 Apr;41(3):536-544. doi: 10.1007/s10875-021-00994-9. Epub 2021 Feb 22. J Clin Immunol. 2021. PMID: 33616813 Free PMC article.
Distinct cytokine profiles associated with COVID-19 severity and mortality.
Dorgham K, Quentric P, Gökkaya M, Marot S, Parizot C, Sauce D, Guihot A, Luyt CE, Schmidt M, Mayaux J, Beurton A, Le Guennec L, Demeret S, Ben Salah E, Mathian A, Yssel H, Combadiere B, Combadiere C, Traidl-Hoffmann C, Burrel S, Marcelin AG, Amoura Z, Voiriot G, Neumann AU, Gorochov G. Dorgham K, et al. Among authors: burrel s. J Allergy Clin Immunol. 2021 Jun;147(6):2098-2107. doi: 10.1016/j.jaci.2021.03.047. Epub 2021 Apr 22. J Allergy Clin Immunol. 2021. PMID: 33894209 Free PMC article. Clinical Trial.
The 501Y.V2 SARS-CoV-2 variant has an intermediate viral load between the 501Y.V1 and the historical variants in nasopharyngeal samples from newly diagnosed COVID-19 patients.
Teyssou E, Soulie C, Visseaux B, Lambert-Niclot S, Ferre V, Marot S, Jary A, Sayon S, Zafilaza K, Leducq V, Schnuriger A, Abdi B, Wirden M, Houhou-Fidouh N, Charpentier C, Morand-Joubert L, Burrel S, Descamps D, Calvez V, Marcelin AG. Teyssou E, et al. Among authors: burrel s. J Infect. 2021 Jul;83(1):119-145. doi: 10.1016/j.jinf.2021.04.023. Epub 2021 Apr 28. J Infect. 2021. PMID: 33932451 Free PMC article. No abstract available.
Neutralization Heterogeneity of UK and South African Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants in BNT162b2-Vaccinated or Convalescent Coronavirus Disease 2019 (COVID-19) Healthcare Workers.
Marot S, Malet I, Leducq V, Abdi B, Teyssou E, Soulie C, Wirden M, Rodriguez C, Fourati S, Pawlotsky JM, Boutolleau D, Burrel S, Calvez V, Marcelin AG, Jary A. Marot S, et al. Among authors: burrel s. Clin Infect Dis. 2022 Mar 1;74(4):707-710. doi: 10.1093/cid/ciab492. Clin Infect Dis. 2022. PMID: 34050731 Free PMC article.
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, K… See abstract for full author list ➔ Bastard P, et al. Among authors: burrel s. Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340. Sci Immunol. 2021. PMID: 34413139 Free PMC article.
106 results