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Skin γδ T cell inflammatory responses are hardwired in the thymus by oxysterol sensing via GPR183 and calibrated by dietary cholesterol.
Frascoli M, Ferraj E, Miu B, Malin J, Spidale NA, Cowan J, Shissler SC, Brink R, Xu Y, Cyster JG, Bhandoola A, Kang J, Reboldi A. Frascoli M, et al. Among authors: bhandoola a. Immunity. 2023 Mar 14;56(3):562-575.e6. doi: 10.1016/j.immuni.2023.01.025. Epub 2023 Feb 25. Immunity. 2023. PMID: 36842431 Free PMC article.
Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut.
Das A, Martinez-Ruiz GU, Bouladoux N, Stacy A, Moraly J, Vega-Sendino M, Zhao Y, Lavaert M, Ding Y, Morales-Sanchez A, Harly C, Seedhom MO, Chari R, Awasthi P, Ikeuchi T, Wang Y, Zhu J, Moutsopoulos NM, Chen W, Yewdell JW, Shapiro VS, Ruiz S, Taylor N, Belkaid Y, Bhandoola A. Das A, et al. Among authors: bhandoola a. Immunity. 2024 Apr 18:S1074-7613(24)00206-1. doi: 10.1016/j.immuni.2024.04.001. Online ahead of print. Immunity. 2024. PMID: 38677292
Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues.
Zheng M, Yao C, Ren G, Mao K, Chung H, Chen X, Hu G, Wang L, Luan X, Fang D, Li D, Zhong C, Lu X, Cannon N, Zhang M, Bhandoola A, Zhao K, O'Shea JJ, Zhu J. Zheng M, et al. Among authors: bhandoola a. Cell Rep. 2023 Aug 29;42(8):112924. doi: 10.1016/j.celrep.2023.112924. Epub 2023 Aug 3. Cell Rep. 2023. PMID: 37540600 Free PMC article.
Bone marrow plasma cells require P2RX4 to sense extracellular ATP.
Ishikawa M, Hasanali ZS, Zhao Y, Das A, Lavaert M, Roman CJ, Londregan J, Allman D, Bhandoola A. Ishikawa M, et al. Among authors: bhandoola a. Nature. 2024 Feb;626(8001):1102-1107. doi: 10.1038/s41586-024-07047-2. Epub 2024 Feb 14. Nature. 2024. PMID: 38355795 Free PMC article.
Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development.
Malin J, Martinez-Ruiz GU, Zhao Y, Shissler SC, Cowan JE, Ding Y, Morales-Sanchez A, Ishikawa M, Lavaert M, Das A, Butcher D, Warner AC, Kallarakal M, Chen J, Kedei N, Kelly M, Brinster LR, Allman D, Bhandoola A. Malin J, et al. Among authors: bhandoola a. Sci Adv. 2023 Nov 17;9(46):eadg8126. doi: 10.1126/sciadv.adg8126. Epub 2023 Nov 15. Sci Adv. 2023. PMID: 37967174 Free PMC article.
Mucosal-associated invariant T cells restrict reactive oxidative damage and preserve meningeal barrier integrity and cognitive function.
Zhang Y, Bailey JT, Xu E, Singh K, Lavaert M, Link VM, D'Souza S, Hafiz A, Cao J, Cao G, Sant'Angelo DB, Sun W, Belkaid Y, Bhandoola A, McGavern DB, Yang Q. Zhang Y, et al. Among authors: bhandoola a. Nat Immunol. 2022 Dec;23(12):1714-1725. doi: 10.1038/s41590-022-01349-1. Epub 2022 Nov 21. Nat Immunol. 2022. PMID: 36411380 Free PMC article.
Early Development of Innate Lymphoid Cells.
Ding Y, Harly C, Das A, Bhandoola A. Ding Y, et al. Among authors: bhandoola a. Methods Mol Biol. 2023;2580:51-69. doi: 10.1007/978-1-0716-2740-2_3. Methods Mol Biol. 2023. PMID: 36374450 Review.
T cell development made EZ.
Lavaert M, Bhandoola A. Lavaert M, et al. Among authors: bhandoola a. Cell Stem Cell. 2022 Aug 4;29(8):1155-1156. doi: 10.1016/j.stem.2022.07.003. Cell Stem Cell. 2022. PMID: 35931025 Free article.
133 results