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379 results

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Page 1
Developmental trajectories and cooperating genomic events define molecular subtypes of BCR::ABL1-positive ALL.
Bastian L, Beder T, Barz MJ, Bendig S, Bartsch L, Walter W, Wolgast N, Brändl B, Rohrandt C, Hansen BT, Hartmann AM, Iben K, Das Gupta D, Denker M, Zimmermann J, Wittig M, Chitadze G, Neumann M, Schneller F, Fiedler W, Steffen B, Stelljes M, Faul C, Schwartz S, Müller FJ, Cario G, Harder L, Haferlach C, Pfeifer H, Gökbuget N, Brüggemann M, Baldus CD. Bastian L, et al. Blood. 2024 Apr 4;143(14):1391-1398. doi: 10.1182/blood.2023021752. Blood. 2024. PMID: 38153913 Free PMC article.
Somatic TP53 mutations are preleukemic events in acute lymphoblastic leukemia.
Chitadze G, Stengel A, John-Klaua C, Bruckmüller J, Trautmann H, Kotrova M, Darzentas F, Kelm M, Pal K, Darzentas N, Bastian L, Kehden B, Wessels W, Ströh AS, Oberg HH, Altrock PM, Baer C, Meggendorfer M, Gökbuget N, Baldus CD, Haferlach C, Brüggemann M. Chitadze G, et al. Among authors: bastian l. Blood. 2023 Mar 30;141(13):1640-1644. doi: 10.1182/blood.2022017249. Blood. 2023. PMID: 36450137 Free PMC article. No abstract available.
The Gene Expression Classifier ALLCatchR Identifies B-cell Precursor ALL Subtypes and Underlying Developmental Trajectories Across Age.
Beder T, Hansen BT, Hartmann AM, Zimmermann J, Amelunxen E, Wolgast N, Walter W, Zaliova M, Antić Ž, Chouvarine P, Bartsch L, Barz MJ, Bultmann M, Horns J, Bendig S, Kässens J, Kaleta C, Cario G, Schrappe M, Neumann M, Gökbuget N, Bergmann AK, Trka J, Haferlach C, Brüggemann M, Baldus CD, Bastian L. Beder T, et al. Among authors: bastian l. Hemasphere. 2023 Aug 25;7(9):e939. doi: 10.1097/HS9.0000000000000939. eCollection 2023 Sep. Hemasphere. 2023. PMID: 37645423 Free PMC article.
PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia.
Bastian L, Schroeder MP, Eckert C, Schlee C, Tanchez JO, Kämpf S, Wagner DL, Schulze V, Isaakidis K, Lázaro-Navarro J, Hänzelmann S, James AR, Ekici A, Burmeister T, Schwartz S, Schrappe M, Horstmann M, Vosberg S, Krebs S, Blum H, Hecht J, Greif PA, Rieger MA, Brüggemann M, Gökbuget N, Neumann M, Baldus CD. Bastian L, et al. Leukemia. 2019 Aug;33(8):1895-1909. doi: 10.1038/s41375-019-0430-z. Epub 2019 Mar 6. Leukemia. 2019. PMID: 30842609
Inhibiting casein kinase 2 sensitizes acute lymphoblastic leukemia cells to venetoclax via MCL1 degradation.
Lázaro-Navarro J, Pimentel-Gutiérrez HJ, Gauert A, Hagemann AIH, Eisenschmid J, Gökbuget N, Vick B, Jeremias I, Seyfried F, Meyer LH, Debatin KM, Richer K, Bultman M, Neumann M, Hänzelmann S, Serve H, Astrahantseff K, Rieger MA, Eckert C, Baldus CD, Bastian L. Lázaro-Navarro J, et al. Among authors: bastian l. Blood Adv. 2021 Dec 28;5(24):5501-5506. doi: 10.1182/bloodadvances.2021004513. Blood Adv. 2021. PMID: 34610112 Free PMC article. No abstract available.
IGH Rearrangement Evolution in Adult KMT2A-rearranged B-cell Precursor ALL: Implications for Cell-of-origin and MRD Monitoring.
Darzentas F, Szczepanowski M, Kotrová M, Kelm M, Hartmann A, Beder T, Gökbuget N, Neumann M, Bastian L, Baldus CD, Pál K, Darzentas N, Brüggemann M. Darzentas F, et al. Among authors: bastian l. Hemasphere. 2022 Dec 20;7(1):e820. doi: 10.1097/HS9.0000000000000820. eCollection 2023 Jan. Hemasphere. 2022. PMID: 36570692 Free PMC article. No abstract available.
UBTF::ATXN7L3 gene fusion defines novel B cell precursor ALL subtype with CDX2 expression and need for intensified treatment.
Bastian L, Hartmann AM, Beder T, Hänzelmann S, Kässens J, Bultmann M, Hoeppner MP, Franzenburg S, Wittig M, Franke A, Nagel I, Spielmann M, Reimer N, Busch H, Schwartz S, Steffen B, Viardot A, Döhner K, Kondakci M, Wulf G, Wendelin K, Renzelmann A, Kiani A, Trautmann H, Neumann M, Gökbuget N, Brüggemann M, Baldus CD. Bastian L, et al. Leukemia. 2022 Jun;36(6):1676-1680. doi: 10.1038/s41375-022-01557-6. Epub 2022 Apr 9. Leukemia. 2022. PMID: 35397658 Free PMC article. No abstract available.
An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse.
Bartsch L, Schroeder MP, Hänzelmann S, Bastian L, Lázaro-Navarro J, Schlee C, Tanchez JO, Schulze V, Isaakidis K, Rieger MA, Gökbuget N, Eckert C, Serve H, Horstmann M, Schrappe M, Brüggemann M, Baldus CD, Neumann M. Bartsch L, et al. Among authors: bastian l. BMC Genom Data. 2022 Apr 18;23(1):30. doi: 10.1186/s12863-022-01041-1. BMC Genom Data. 2022. PMID: 35436854 Free PMC article.
Combining daratumumab with CD47 blockade prolongs survival in preclinical models of pediatric T-ALL.
Müller K, Vogiatzi F, Winterberg D, Rösner T, Lenk L, Bastian L, Gehlert CL, Autenrieb MP, Brüggemann M, Cario G, Schrappe M, Kulozik AE, Eckert C, Bergmann AK, Bornhauser B, Bourquin JP, Valerius T, Peipp M, Kellner C, Schewe DM. Müller K, et al. Among authors: bastian l. Blood. 2022 Jul 7;140(1):45-57. doi: 10.1182/blood.2021014485. Blood. 2022. PMID: 35452517 Free article.
379 results