UBTF::ATXN7L3 gene fusion defines novel B cell precursor ALL subtype with CDX2 expression and need for intensified treatment

Affiliations

• ¹ Medical Department II, Hematology and Oncology, University Medical Center Schleswig-Holstein, Kiel, Germany.
• ² University Cancer Center Schleswig-Holstein, University Medical Center Schleswig-Holstein, Kiel and Lübeck, Germany.
• ³ Clinical Research Unit "CATCH-ALL" (KFO 5010/1), funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Bonn, Germany.
• ⁴ Institute for Clinical Molecular Biology, Kiel University, Kiel, Germany.
• ⁵ Institute of Human Genetics, University Medical Center Schleswig-Holstein, Kiel & Lübeck, Germany.
• ⁶ DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Lübeck/Kiel, 23538, Lübeck, Germany.
• ⁷ Medical Systems Biology Group and Institute for Cardiogenetics, University of Lübeck, Lübeck, Germany.
• ⁸ University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
• ⁹ Department of Hematology, Oncology and Tumor Immunology (Campus Benjamin Franklin), Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
• ¹⁰ Department of Medicine II, Hematology/Oncology, Goethe University Hospital, Frankfurt/M, Germany.
• ¹¹ Department of Internal Medicine III, University Hospital Ulm, Ulm, Germany.
• ¹² Department of Hematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Düsseldorf, Germany.
• ¹³ Department of Hematology and Oncology, University Hospital Göttingen, Göttingen, Germany.
• ¹⁴ Medical Department V, Hospital Nürnberg, Paracelsus Medizinische Privatuniversität, Nürnberg, Germany.
• ¹⁵ Medical Department Oncology and Hematology, University Medical Center Oldenburg, Oldenburg, Germany.
• ¹⁶ Department of Medicine IV, Hematology/Oncology, Klinikum Bayreuth, Bayreuth, Germany.
• ¹⁷ Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany.
• ¹⁸ Medical Department II, Hematology and Oncology, University Medical Center Schleswig-Holstein, Kiel, Germany. Claudia.baldus@uksh.de.
• ¹⁹ University Cancer Center Schleswig-Holstein, University Medical Center Schleswig-Holstein, Kiel and Lübeck, Germany. Claudia.baldus@uksh.de.
• ²⁰ Clinical Research Unit "CATCH-ALL" (KFO 5010/1), funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Bonn, Germany. Claudia.baldus@uksh.de.