miR-34c-5p modulates X-box-binding protein 1 (XBP1) expression during the adaptive phase of the unfolded protein response.
Bartoszewska S, Cabaj A, Dąbrowski M, Collawn JF, Bartoszewski R.
Bartoszewska S, et al.
FASEB J. 2019 Oct;33(10):11541-11554. doi: 10.1096/fj.201900600RR. Epub 2019 Jul 17.
FASEB J. 2019.
PMID: 31314593
Free PMC article.
During endoplasmic reticulum (ER) stress conditions, an adaptive signaling network termed the unfolded protein response (UPR) is activated. The UPR's function is to increase ER protein-folding capacity in order to attenuate ER stress, restore ER homeostasis, and, most impo …
During endoplasmic reticulum (ER) stress conditions, an adaptive signaling network termed the unfolded protein response (UPR) is activated. …