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Point mutations in the PDX1 transactivation domain impair human β-cell development and function.
Wang X, Sterr M, Ansarullah, Burtscher I, Böttcher A, Beckenbauer J, Siehler J, Meitinger T, Häring HU, Staiger H, Cernilogar FM, Schotta G, Irmler M, Beckers J, Wright CVE, Bakhti M, Lickert H. Wang X, et al. Among authors: bakhti m. Mol Metab. 2019 Jun;24:80-97. doi: 10.1016/j.molmet.2019.03.006. Epub 2019 Mar 20. Mol Metab. 2019. PMID: 30930126 Free PMC article.
Identification of proliferative and mature β-cells in the islets of Langerhans.
Bader E, Migliorini A, Gegg M, Moruzzi N, Gerdes J, Roscioni SS, Bakhti M, Brandl E, Irmler M, Beckers J, Aichler M, Feuchtinger A, Leitzinger C, Zischka H, Wang-Sattler R, Jastroch M, Tschöp M, Machicao F, Staiger H, Häring HU, Chmelova H, Chouinard JA, Oskolkov N, Korsgren O, Speier S, Lickert H. Bader E, et al. Among authors: bakhti m. Nature. 2016 Jul 21;535(7612):430-4. doi: 10.1038/nature18624. Epub 2016 Jul 11. Nature. 2016. PMID: 27398620
Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.
Quarta C, Clemmensen C, Zhu Z, Yang B, Joseph SS, Lutter D, Yi CX, Graf E, García-Cáceres C, Legutko B, Fischer K, Brommage R, Zizzari P, Franklin BS, Krueger M, Koch M, Vettorazzi S, Li P, Hofmann SM, Bakhti M, Bastidas-Ponce A, Lickert H, Strom TM, Gailus-Durner V, Bechmann I, Perez-Tilve D, Tuckermann J, Hrabě de Angelis M, Sandoval D, Cota D, Latz E, Seeley RJ, Müller TD, DiMarchi RD, Finan B, Tschöp MH. Quarta C, et al. Among authors: bakhti m. Cell Metab. 2017 Oct 3;26(4):620-632.e6. doi: 10.1016/j.cmet.2017.08.023. Epub 2017 Sep 21. Cell Metab. 2017. PMID: 28943448 Free article.
Animal models of obesity and diabetes mellitus.
Kleinert M, Clemmensen C, Hofmann SM, Moore MC, Renner S, Woods SC, Huypens P, Beckers J, de Angelis MH, Schürmann A, Bakhti M, Klingenspor M, Heiman M, Cherrington AD, Ristow M, Lickert H, Wolf E, Havel PJ, Müller TD, Tschöp MH. Kleinert M, et al. Among authors: bakhti m. Nat Rev Endocrinol. 2018 Mar;14(3):140-162. doi: 10.1038/nrendo.2017.161. Epub 2018 Jan 19. Nat Rev Endocrinol. 2018. PMID: 29348476 Review.
Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.
Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, Staiger H, Häring HU, Lederer G, Meitinger T, Cernilogar FM, Schotta G, Irmler M, Beckers J, Hrabě de Angelis M, Ray M, Wright CVE, Bakhti M, Lickert H. Wang X, et al. Among authors: bakhti m. Mol Metab. 2018 Mar;9:57-68. doi: 10.1016/j.molmet.2018.01.011. Epub 2018 Jan 31. Mol Metab. 2018. PMID: 29396371 Free PMC article.
Inferring population dynamics from single-cell RNA-sequencing time series data.
Fischer DS, Fiedler AK, Kernfeld EM, Genga RMJ, Bastidas-Ponce A, Bakhti M, Lickert H, Hasenauer J, Maehr R, Theis FJ. Fischer DS, et al. Among authors: bakhti m. Nat Biotechnol. 2019 Apr;37(4):461-468. doi: 10.1038/s41587-019-0088-0. Epub 2019 Apr 1. Nat Biotechnol. 2019. PMID: 30936567 Free PMC article.
Sorting Out Fate Determination.
Bakhti M, Bastidas-Ponce A, Lickert H. Bakhti M, et al. Dev Cell. 2019 Apr 8;49(1):1-3. doi: 10.1016/j.devcel.2019.03.020. Dev Cell. 2019. PMID: 30965032 Free article.
47 results