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Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody.
Macías-León J , Bermejo IA , Asín A , García-García A , Compañón I , Jiménez-Moreno E , Coelho H , Mangini V , Albuquerque IS , Marcelo F , Asensio JL , Bernardes GJL , Joshi HJ , Fiammengo R , Blixt O , Hurtado-Guerrero R , Corzana F . Macías-León J , et al. Among authors: asensio jl. Chem Commun (Camb). 2020 Dec 8;56(96):15137-15140. doi: 10.1039/d0cc06349e. Chem Commun (Camb). 2020. PMID: 33211039
A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4.
Asensio JL, Hidalgo A, Bastida A, Torrado M, Corzana F, Chiara JL, García-Junceda E, Cañada J, Jiménez-Barbero J. Asensio JL, et al. J Am Chem Soc. 2005 Jun 15;127(23):8278-9. doi: 10.1021/ja051722z. J Am Chem Soc. 2005. PMID: 15941249 Free article.
A simple NMR analysis of the protonation equilibrium that accompanies aminoglycoside recognition: dramatic alterations in the neomycin-B protonation state upon binding to a 23-mer RNA aptamer.
Freire F, Cuesta I, Corzana F, Revuelta J, González C, Hricovini M, Bastida A, Jiménez-Barbero J, Asensio JL. Freire F, et al. Among authors: asensio jl. Chem Commun (Camb). 2007 Jan 14;(2):174-6. doi: 10.1039/b611597g. Epub 2006 Oct 23. Chem Commun (Camb). 2007. PMID: 17180237
87 results