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A combined approach of structure-based virtual screening and NMR to interrupt the PD-1/PD-L1 axis: Biphenyl-benzimidazole containing compounds as novel PD-L1 inhibitors.
Donati G, Viviano M, D'Amore VM, Cipriano A, Diakogiannaki I, Amato J, Tomassi S, Brancaccio D, Russomanno P, Di Leva FS, Arosio D, Seneci P, Taliani S, Magiera-Mularz K, Musielak B, Skalniak L, Holak TA, Castellano S, La Pietra V, Marinelli L. Donati G, et al. Among authors: arosio d. Arch Pharm (Weinheim). 2024 Mar;357(3):e2300583. doi: 10.1002/ardp.202300583. Epub 2023 Dec 18. Arch Pharm (Weinheim). 2024. PMID: 38110703 Free article.
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design.
Donati G, D'Amore VM, Russomanno P, Cerofolini L, Amato J, Marzano S, Salobehaj M, Rizzo D, Assoni G, Carotenuto A, La Pietra V, Arosio D, Seneci P, Fragai M, Brancaccio D, Di Leva FS, Marinelli L. Donati G, et al. Among authors: arosio d. Comput Struct Biotechnol J. 2023 Jun 8;21:3355-3368. doi: 10.1016/j.csbj.2023.06.006. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 37384351 Free PMC article.
HuR modulation counteracts lipopolysaccharide response in murine macrophages.
Bonomo I, Assoni G, La Pietra V, Canarutto G, Facen E, Donati G, Zucal C, Genovese S, Micaelli M, Pérez-Ràfols A, Robbiati S, Kontoyannis DL, De Matteo M, Fragai M, Seneci P, Marinelli L, Arosio D, Piazza S, Provenzani A. Bonomo I, et al. Among authors: arosio d. Dis Model Mech. 2023 Mar 1;16(3):dmm050120. doi: 10.1242/dmm.050120. Epub 2023 Mar 29. Dis Model Mech. 2023. PMID: 36912171 Free PMC article.
An optimized SpCas9 high-fidelity variant for direct protein delivery.
Pedrazzoli E, Bianchi A, Umbach A, Amistadi S, Brusson M, Frati G, Ciciani M, Badowska KA, Arosio D, Miccio A, Cereseto A, Casini A. Pedrazzoli E, et al. Among authors: arosio d. Mol Ther. 2023 Jul 5;31(7):2257-2265. doi: 10.1016/j.ymthe.2023.03.007. Epub 2023 Mar 10. Mol Ther. 2023. PMID: 36905119 Free article.
Genetically encoded sensors for Chloride concentration.
Lodovichi C, Ratto GM, Trevelyan AJ, Arosio D. Lodovichi C, et al. Among authors: arosio d. J Neurosci Methods. 2022 Feb 15;368:109455. doi: 10.1016/j.jneumeth.2021.109455. Epub 2021 Dec 22. J Neurosci Methods. 2022. PMID: 34952088 Review.
HuR-targeted agents: An insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models.
Assoni G, La Pietra V, Digilio R, Ciani C, Licata NV, Micaelli M, Facen E, Tomaszewska W, Cerofolini L, Pérez-Ràfols A, Varela Rey M, Fragai M, Woodhoo A, Marinelli L, Arosio D, Bonomo I, Provenzani A, Seneci P. Assoni G, et al. Among authors: arosio d. Adv Drug Deliv Rev. 2022 Feb;181:114088. doi: 10.1016/j.addr.2021.114088. Epub 2021 Dec 20. Adv Drug Deliv Rev. 2022. PMID: 34942276 Review.
105 results