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Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets.
Wang X, Palasubramaniam J, Gkanatsas Y, Hohmann JD, Westein E, Kanojia R, Alt K, Huang D, Jia F, Ahrens I, Medcalf RL, Peter K, Hagemeyer CE. Wang X, et al. Among authors: alt k. Circ Res. 2014 Mar 28;114(7):1083-93. doi: 10.1161/CIRCRESAHA.114.302514. Epub 2014 Feb 9. Circ Res. 2014. PMID: 24508759
Engineering poly(ethylene glycol) particles for improved biodistribution.
Cui J, De Rose R, Alt K, Alcantara S, Paterson BM, Liang K, Hu M, Richardson JJ, Yan Y, Jeffery CM, Price RI, Peter K, Hagemeyer CE, Donnelly PS, Kent SJ, Caruso F. Cui J, et al. Among authors: alt k. ACS Nano. 2015 Feb 24;9(2):1571-80. doi: 10.1021/nn5061578. Epub 2015 Jan 21. ACS Nano. 2015. PMID: 25712853
A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry.
Alt K, Paterson BM, Westein E, Rudd SE, Poniger SS, Jagdale S, Ardipradja K, Connell TU, Krippner GY, Nair AK, Wang X, Tochon-Danguy HJ, Donnelly PS, Peter K, Hagemeyer CE. Alt K, et al. Angew Chem Int Ed Engl. 2015 Jun 22;54(26):7515-9. doi: 10.1002/anie.201411507. Epub 2015 May 11. Angew Chem Int Ed Engl. 2015. PMID: 25962581
185 results