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A novel class of phenylpyrazolone-sulphonamides rigid synthetic anticancer molecules selectively inhibit the isoform IX of carbonic anhydrases guided by molecular docking and orbital analyses.
Khayat MT, Ahmed HEA, Omar AM, Muhammad YA, Mohammad KA, Malebari AM, Khayyat AN, Halawa AH, Abulkhair HS, Al-Karmalawy AA, Almaghrabi M, Alharbi M, Aljahdali AS, El-Agrody AM. Khayat MT, et al. Among authors: almaghrabi m. J Biomol Struct Dyn. 2023;41(24):15243-15261. doi: 10.1080/07391102.2023.2188957. Epub 2023 Mar 13. J Biomol Struct Dyn. 2023. PMID: 36914238
Introducing of novel class of pyrano[2,3-c]pyrazole-5-carbonitrile analogs with potent antimicrobial activity, DNA gyrase inhibition, and prominent pharmacokinetic and CNS toxicity profiles supported by molecular dynamic simulation.
Almaghrabi M, Musa A, Aljohani AKB, Ahmed HEA, Alsulaimany M, Miski SF, Mostafa EM, Hussein S, Parambi DGT, Ghoneim MM, Elgammal WE, Halawa AH, Hammad A, El-Agrody AM. Almaghrabi M, et al. J Biomol Struct Dyn. 2023 Sep 3:1-18. doi: 10.1080/07391102.2023.2252088. Online ahead of print. J Biomol Struct Dyn. 2023. PMID: 37661733
Development of Novel Class of Phenylpyrazolo[3,4-d]pyrimidine-Based Analogs with Potent Anticancer Activity and Multitarget Enzyme Inhibition Supported by Docking Studies.
Aljohani AKB, El Zaloa WAZ, Alswah M, Seleem MA, Elsebaei MM, Bayoumi AH, El-Morsy AM, Almaghrabi M, Awaji AA, Hammad A, Alsulaimany M, Ahmed HEA. Aljohani AKB, et al. Among authors: almaghrabi m. Int J Mol Sci. 2023 Oct 9;24(19):15026. doi: 10.3390/ijms241915026. Int J Mol Sci. 2023. PMID: 37834474 Free PMC article.
Prevalence of multi-drug resistant bacteria in intensive care units at Tripoli University Hospital, Tripoli, Libya.
Ibrahim K, Thwood D, ELgheriani H, Salem M, Elgadiym Z, Zaghdani A, Alhudiri I, Habibi A, Elfahem A, Belaid S, Ermithi O, Almaghrabi M, ELmaryul A, Almadah S, Rayes A, El Meshri SE, El Salabi A, Elzagheid A. Ibrahim K, et al. Among authors: almaghrabi m. Libyan J Med. 2024 Dec 31;19(1):2348235. doi: 10.1080/19932820.2024.2348235. Epub 2024 May 8. Libyan J Med. 2024. PMID: 38718270 Free PMC article.
75 results