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Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.
Alizadeh J, Zeki AA, Mirzaei N, Tewary S, Rezaei Moghadam A, Glogowska A, Nagakannan P, Eftekharpour E, Wiechec E, Gordon JW, Xu FY, Field JT, Yoneda KY, Kenyon NJ, Hashemi M, Hatch GM, Hombach-Klonisch S, Klonisch T, Ghavami S. Alizadeh J, et al. Sci Rep. 2017 Mar 27;7:44841. doi: 10.1038/srep44841. Sci Rep. 2017. PMID: 28344327 Free PMC article.
New frontiers in the treatment of colorectal cancer: Autophagy and the unfolded protein response as promising targets.
Mokarram P, Albokashy M, Zarghooni M, Moosavi MA, Sepehri Z, Chen QM, Hudecki A, Sargazi A, Alizadeh J, Moghadam AR, Hashemi M, Movassagh H, Klonisch T, Owji AA, Łos MJ, Ghavami S. Mokarram P, et al. Among authors: alizadeh j. Autophagy. 2017 May 4;13(5):781-819. doi: 10.1080/15548627.2017.1290751. Epub 2017 Feb 23. Autophagy. 2017. PMID: 28358273 Free PMC article. Review.
Statins: a new approach to combat temozolomide chemoresistance in glioblastoma.
Shojaei S, Alizadeh J, Thliveris J, Koleini N, Kardami E, Hatch GM, Xu F, Hombach-Klonisch S, Klonisch T, Ghavami S. Shojaei S, et al. Among authors: alizadeh j. J Investig Med. 2018 Dec;66(8):1083-1087. doi: 10.1136/jim-2018-000874. Epub 2018 Oct 27. J Investig Med. 2018. PMID: 30368483 Review.
Mechanisms Targeting the Unfolded Protein Response in Asthma.
Dastghaib S, Kumar PS, Aftabi S, Damera G, Dalvand A, Sepanjnia A, Kiumarsi M, Aghanoori MR, Sohal SS, Ande SR, Alizadeh J, Mokarram P, Ghavami S, Sharma P, Zeki AA. Dastghaib S, et al. Among authors: alizadeh j. Am J Respir Cell Mol Biol. 2021 Jan;64(1):29-38. doi: 10.1165/rcmb.2019-0235TR. Am J Respir Cell Mol Biol. 2021. PMID: 32915643 Review.
Pleiotropic effects of statins: A focus on cancer.
Ahmadi M, Amiri S, Pecic S, Machaj F, Rosik J, Łos MJ, Alizadeh J, Mahdian R, da Silva Rosa SC, Schaafsma D, Shojaei S, Madrakian T, Zeki AA, Ghavami S. Ahmadi M, et al. Among authors: alizadeh j. Biochim Biophys Acta Mol Basis Dis. 2020 Dec 1;1866(12):165968. doi: 10.1016/j.bbadis.2020.165968. Epub 2020 Sep 12. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 32927022 Free article. Review.
Simvastatin increases temozolomide-induced cell death by targeting the fusion of autophagosomes and lysosomes.
Shojaei S, Koleini N, Samiei E, Aghaei M, Cole LK, Alizadeh J, Islam MI, Vosoughi AR, Albokashy M, Butterfield Y, Marzban H, Xu F, Thliveris J, Kardami E, Hatch GM, Eftekharpour E, Akbari M, Hombach-Klonisch S, Klonisch T, Ghavami S. Shojaei S, et al. Among authors: alizadeh j. FEBS J. 2020 Mar;287(5):1005-1034. doi: 10.1111/febs.15069. Epub 2019 Oct 14. FEBS J. 2020. PMID: 31545550 Free article.
45 results