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Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum-to-mitochondria Ca2+ transfer for survival.
Cardenas C, Lovy A, Silva-Pavez E, Urra F, Mizzoni C, Ahumada-Castro U, Bustos G, Jaňa F, Cruz P, Farias P, Mendoza E, Huerta H, Murgas P, Hunter M, Rios M, Cerda O, Georgakoudi I, Zakarian A, Molgó J, Foskett JK. Cardenas C, et al. Among authors: ahumada castro u. Sci Signal. 2020 Jul 14;13(640):eaay1212. doi: 10.1126/scisignal.aay1212. Sci Signal. 2020. PMID: 32665411 Free PMC article.
Ca2+ transfer to mitochondria: a spark of life in unexpected conditions.
Silva-Pavez E, Ahumada-Castro U, Lovy A, Cárdenas JC. Silva-Pavez E, et al. Among authors: ahumada castro u. Mol Cell Oncol. 2020 Dec 15;8(1):1839341. doi: 10.1080/23723556.2020.1839341. eCollection 2021. Mol Cell Oncol. 2020. PMID: 33553601 Free PMC article.
Keeping zombies alive: The ER-mitochondria Ca2+ transfer in cellular senescence.
Ahumada-Castro U, Puebla-Huerta A, Cuevas-Espinoza V, Lovy A, Cardenas JC. Ahumada-Castro U, et al. Biochim Biophys Acta Mol Cell Res. 2021 Oct;1868(11):119099. doi: 10.1016/j.bbamcr.2021.119099. Epub 2021 Jul 16. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 34274397 Free article. Review.
FR58P1a; a new uncoupler of OXPHOS that inhibits migration in triple-negative breast cancer cells via Sirt1/AMPK/β1-integrin pathway.
Urra FA, Muñoz F, Córdova-Delgado M, Ramírez MP, Peña-Ahumada B, Rios M, Cruz P, Ahumada-Castro U, Bustos G, Silva-Pavez E, Pulgar R, Morales D, Varela D, Millas-Vargas JP, Retamal E, Ramírez-Rodríguez O, Pessoa-Mahana H, Pavani M, Ferreira J, Cárdenas C, Araya-Maturana R. Urra FA, et al. Sci Rep. 2018 Sep 4;8(1):13190. doi: 10.1038/s41598-018-31367-9. Sci Rep. 2018. PMID: 30181620 Free PMC article.
14 results