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Gold(I) Phosphine Derivatives with Improved Selectivity as Topically Active Drug Leads to Overcome 5-Nitroheterocyclic Drug Resistance in Trichomonas vaginalis.
Miyamoto Y, Aggarwal S, Celaje JJA, Ihara S, Ang J, Eremin DB, Land KM, Wrischnik LA, Zhang L, Fokin VV, Eckmann L. Miyamoto Y, et al. Among authors: aggarwal s. J Med Chem. 2021 May 27;64(10):6608-6620. doi: 10.1021/acs.jmedchem.0c01926. Epub 2021 May 11. J Med Chem. 2021. PMID: 33974434 Free PMC article.
Virtual Screening of a Chemically Diverse "Superscaffold" Library Enables Ligand Discovery for a Key GPCR Target.
Grotsch K, Sadybekov AV, Hiller S, Zaidi S, Eremin D, Le A, Liu Y, Smith EC, Illiopoulis-Tsoutsouvas C, Thomas J, Aggarwal S, Pickett JE, Reyes C, Picazo E, Roth BL, Makriyannis A, Katritch V, Fokin VV. Grotsch K, et al. Among authors: aggarwal s. ACS Chem Biol. 2024 Apr 19;19(4):866-874. doi: 10.1021/acschembio.3c00602. Epub 2024 Apr 10. ACS Chem Biol. 2024. PMID: 38598723
Inflammatory lung injury is associated with endothelial cell mitochondrial fission and requires the nitration of RhoA and cytoskeletal remodeling.
Pokharel MD, Fu P, Garcia-Flores A, Yegambaram M, Lu Q, Sun X, Unwalla H, Aggarwal S, Fineman JR, Wang T, Black SM. Pokharel MD, et al. Among authors: aggarwal s. Free Radic Biol Med. 2024 May 9:S0891-5849(24)00454-4. doi: 10.1016/j.freeradbiomed.2024.05.019. Online ahead of print. Free Radic Biol Med. 2024. PMID: 38734269
2,481 results