COVID-19 vaccine hesitancy among adults in India: A primary study based on health behavior theories and 5C psychological antecedents model

PLoS One. 2024 May 9;19(5):e0294480. doi: 10.1371/journal.pone.0294480. eCollection 2024.

Abstract

Despite the significant success of India's COVID-19 vaccination program, a sizeable proportion of the adult population remains unvaccinated or has received a single dose of the vaccine. Despite the recommendations of the Government of India for the two doses of the COVID-19 vaccine and the precautionary booster dose, many people were still hesitant towards the COVID-19 full vaccination. Hence, this study aimed to identify the primary behavioral and psychological factors contributing to vaccine hesitancy. Cross-sectional data was collected via a multi-stage sampling design by using a scheduled sample survey in the Gorakhpur district of Uttar Pradesh, India, between 15 July 2022 to 30 September 2022. This study has utilized three health behavior models-the Health Belief Model (HBM), the Theory of Planned Behavior (TPB), and the 5C Psychological Antecedents of vaccination, and employed bivariate and multivariable binary logistic regression model to assess the level of vaccine hesitancy and predictive health behavior of the respondents. Results indicate that among the constructs of the HBM and 5C Antecedents models, "perceived benefits", "confidence" and "collective responsibility" showed a lesser likelihood of COVID-19 vaccine hesitancy. However, in the TPB model constructs, a 'negative attitude towards the vaccine' showed a four times higher likelihood of COVID-19 vaccine hesitancy. From the future policy perspective, this study suggested that addressing the issue of 'negative attitudes towards the vaccine' and increasing the trust or confidence for the vaccine through increasing awareness about the benefits of the vaccination in India may reduce vaccine hesitancy.

MeSH terms

  • Adolescent
  • Adult
  • COVID-19 Vaccines* / administration & dosage
  • COVID-19* / epidemiology
  • COVID-19* / prevention & control
  • COVID-19* / psychology
  • Cross-Sectional Studies
  • Female
  • Health Behavior*
  • Health Belief Model
  • Health Knowledge, Attitudes, Practice
  • Humans
  • India
  • Male
  • Middle Aged
  • SARS-CoV-2 / immunology
  • Surveys and Questionnaires
  • Vaccination / psychology
  • Vaccination Hesitancy* / psychology
  • Vaccination Hesitancy* / statistics & numerical data
  • Young Adult

Substances

  • COVID-19 Vaccines

Grants and funding

This study was funded by the Indian Council of Medical Research (ICMR), New Delhi, India. However, the funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.