210753/Z/18/Z/WT_/Wellcome Trust/United Kingdom[Grants and Funding] - Search Results

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Year	Number of Results
2018	2
2019	2
2020	2
2021	1
2022	2
2023	3
2024	2

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Design and high-throughput implementation of MALDI-TOF/MS-based assays for Parkin E3 ligase activity.

Traynor R, Moran J, Stevens M, Antico O, Knebel A, Behrouz B, Merchant K, Hastie CJ, Davies P, Muqit MMK, De Cesare V. Traynor R, et al. Cell Rep Methods. 2024 Feb 26;4(2):100712. doi: 10.1016/j.crmeth.2024.100712. Epub 2024 Feb 20. Cell Rep Methods. 2024. PMID: 38382522 Free PMC article.

Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue.

Watzlawik JO, Hou X, Richardson T, Lewicki SL, Siuda J, Wszolek ZK, Cook CN, Petrucelli L, DeTure M, Dickson DW, Antico O, Muqit MMK, Fishman JB, Pirani K, Kumaran R, Polinski NK, Fiesel FC, Springer W. Watzlawik JO, et al. bioRxiv [Preprint]. 2024 Jan 16:2024.01.15.575715. doi: 10.1101/2024.01.15.575715. bioRxiv. 2024. PMID: 38293125 Free PMC article. Preprint.

Whole proteome copy number dataset in primary mouse cortical neurons.

Antico O, Nirujogi RS, Muqit MMK. Antico O, et al. Data Brief. 2023 Jun 23;49:109336. doi: 10.1016/j.dib.2023.109336. eCollection 2023 Aug. Data Brief. 2023. PMID: 37456110 Free PMC article.

Role of Autophagy Pathway in Parkinson's Disease and Related Genetic Neurological Disorders.

Themistokleous C, Bagnoli E, Parulekar R, Muqit MMK. Themistokleous C, et al. J Mol Biol. 2023 Jun 15;435(12):168144. doi: 10.1016/j.jmb.2023.168144. Epub 2023 May 13. J Mol Biol. 2023. PMID: 37182812 Free article. Review.

Structure-based design and characterization of Parkin-activating mutations.

Stevens MU, Croteau N, Eldeeb MA, Antico O, Zeng ZW, Toth R, Durcan TM, Springer W, Fon EA, Muqit MM, Trempe JF. Stevens MU, et al. Life Sci Alliance. 2023 Mar 20;6(6):e202201419. doi: 10.26508/lsa.202201419. Print 2023 Jun. Life Sci Alliance. 2023. PMID: 36941054 Free PMC article.

Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cells.

Kakade P, Ojha H, Raimi OG, Shaw A, Waddell AD, Ault JR, Burel S, Brockmann K, Kumar A, Ahangar MS, Krysztofinska EM, Macartney T, Bayliss R, Fitzgerald JC, Muqit MMK. Kakade P, et al. Open Biol. 2022 Jan;12(1):210264. doi: 10.1098/rsob.210264. Epub 2022 Jan 19. Open Biol. 2022. PMID: 35042401 Free PMC article.

PTEN-induced kinase 1 (PINK1) and Parkin: Unlocking a mitochondrial quality control pathway linked to Parkinson's disease.

Agarwal S, Muqit MMK. Agarwal S, et al. Curr Opin Neurobiol. 2022 Feb;72:111-119. doi: 10.1016/j.conb.2021.09.005. Epub 2021 Oct 27. Curr Opin Neurobiol. 2022. PMID: 34717133 Free article. Review.

Parkinson's: A Disease of Aberrant Vesicle Trafficking.

Singh PK, Muqit MMK. Singh PK, et al. Annu Rev Cell Dev Biol. 2020 Oct 6;36:237-264. doi: 10.1146/annurev-cellbio-100818-125512. Epub 2020 Aug 4. Annu Rev Cell Dev Biol. 2020. PMID: 32749865 Free article. Review.

PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72.

Vieweg S, Mulholland K, Bräuning B, Kachariya N, Lai YC, Toth R, Singh PK, Volpi I, Sattler M, Groll M, Itzen A, Muqit MMK. Vieweg S, et al. Biochem J. 2020 May 15;477(9):1651-1668. doi: 10.1042/BCJ20190664. Biochem J. 2020. PMID: 32227113 Free PMC article.

Therapeutic approaches to enhance PINK1/Parkin mediated mitophagy for the treatment of Parkinson's disease.

Miller S, Muqit MMK. Miller S, et al. Neurosci Lett. 2019 Jul 13;705:7-13. doi: 10.1016/j.neulet.2019.04.029. Epub 2019 Apr 14. Neurosci Lett. 2019. PMID: 30995519 Free article. Review.

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