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Hedgehog pathway plays a vital role in HIV-induced epithelial-mesenchymal transition of podocyte.
Lan X, Wen H, Cheng K, Plagov A, Marashi Shoshtari SS, Malhotra A, Singhal PC. Lan X, et al. Exp Cell Res. 2017 Mar 15;352(2):193-201. doi: 10.1016/j.yexcr.2017.01.019. Epub 2017 Jan 31. Exp Cell Res. 2017. PMID: 28159470 Free PMC article.
Western blotting and real time PCR results showed that renal tissue expression of hedgehog pathway related molecules, including hedgehog homologous (Shh, Ihh, Dhh), PTCH, and Gli1, were increased in HIVAN (Tg26) mice; while immunofluorescent staining displayed localization PTCH e …
Western blotting and real time PCR results showed that renal tissue expression of hedgehog pathway related molecules, including hedgehog hom …
Outcomes of a radiation sparing approach in medulloblastoma by subgroup in young children: an institutional review.
Ronsley R, Triscott J, Stanek J, Rassekh SR, Lum A, Cheng S, Goddard K, McConnell D, Strahlendorf C, Singhal A, Finlay JL, Yip S, Dunham C, Hukin J. Ronsley R, et al. Childs Nerv Syst. 2023 Aug;39(8):2095-2104. doi: 10.1007/s00381-023-05918-z. Epub 2023 Apr 6. Childs Nerv Syst. 2023. PMID: 37022464 Free PMC article.
RESULTS: There were 30 patients (median age 2.8 years, 60% male) treated for medulloblastoma with a radiation-sparing approach at BCCH. Subgroups included Sonic Hedgehog (SHH) (n = 14), group 3 (n = 7), group 4 (n = 6), and indeterminate status (n = 3). ...
RESULTS: There were 30 patients (median age 2.8 years, 60% male) treated for medulloblastoma with a radiation-sparing approach at BCCH. Subg …
Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children.
Triscott J, Lee C, Foster C, Manoranjan B, Pambid MR, Berns R, Fotovati A, Venugopal C, O'Halloran K, Narendran A, Hawkins C, Ramaswamy V, Bouffet E, Taylor MD, Singhal A, Hukin J, Rassekh R, Yip S, Northcott P, Singh SK, Dunham C, Dunn SE. Triscott J, et al. Cancer Res. 2013 Nov 15;73(22):6734-44. doi: 10.1158/0008-5472.CAN-12-4331. Epub 2013 Sep 9. Cancer Res. 2013. PMID: 24019381
This disease is heterogeneous and is composed of four subtypes of medulloblastoma [WNT, Sonic Hedgehog (SHH), Group 3, and Group 4]. An immediate goal is to identify novel molecular targets for the most aggressive forms of medulloblastoma. ...
This disease is heterogeneous and is composed of four subtypes of medulloblastoma [WNT, Sonic Hedgehog (SHH), Group 3, and Group 4]. …
Streptomycin induced protein expression analysis in Mycobacterium tuberculosis by two-dimensional gel electrophoresis & mass spectrometry.
Sharma P, Kumar B, Singhal N, Katoch VM, Venkatesan K, Chauhan DS, Bisht D. Sharma P, et al. Indian J Med Res. 2010 Oct;132:400-8. Indian J Med Res. 2010. PMID: 20966518 Free article.
METHODS: A clinical isolate of M. tuberculosis from Mycobacterial Repository Centre at the Institute (NJIL & OMD), Agra was grown in Sauton's medium for 36 h with/without subinhibitory concentration of the drug (2 mug/ml) and the cell lysate of isolates was prepared by son
METHODS: A clinical isolate of M. tuberculosis from Mycobacterial Repository Centre at the Institute (NJIL & OMD), Agra was grown in Sau …
Extraction of Lipids from Chlorella saccharophila Using High-Pressure Homogenization Followed by Three Phase Partitioning.
Mulchandani K, Kar JR, Singhal RS. Mulchandani K, et al. Appl Biochem Biotechnol. 2015 Jul;176(6):1613-26. doi: 10.1007/s12010-015-1665-4. Epub 2015 May 13. Appl Biochem Biotechnol. 2015. PMID: 25969157
The use of three phase partitioning (TPP) as a green approach for extraction of lipids from Chlorella saccharophila was investigated. Cells disrupted by probe sonication were used for separation of lipids by TPP. The TPP-optimized conditions of 30 % ammonium sulfate, using …
The use of three phase partitioning (TPP) as a green approach for extraction of lipids from Chlorella saccharophila was investigated. Cells …