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Showing results for zika jiang
Search for Zikai Jiang instead (2 results)
Transcriptomic reveals the ferroptosis features of host response in a mouse model of Zika virus infection.
Yan Q, Zheng W, Jiang Y, Zhou P, Lai Y, Liu C, Wu P, Zhuang H, Huang H, Li G, Zhan S, Lao Z, Liu X. Yan Q, et al. J Med Virol. 2023 Jan;95(1):e28386. doi: 10.1002/jmv.28386. J Med Virol. 2023. PMID: 36477858
Zika virus (ZIKV) is a neurotropic flavivirus. The outbreak of ZIKV in 2016 created a global health emergency. ...CYBB, HMOX1, SALT, and SLAC40A1 were selected as potential biomarkers of ZIKV infection. Finally, we validated our results using RT-qPCR and outs
Zika virus (ZIKV) is a neurotropic flavivirus. The outbreak of ZIKV in 2016 created a global health emergency. ...CYBB, HMOX1,
Aberrant NAD(+) metabolism underlies Zika virus-induced microcephaly.
Pang H, Jiang Y, Li J, Wang Y, Nie M, Xiao N, Wang S, Song Z, Ji F, Chang Y, Zheng Y, Yao K, Yao L, Li S, Li P, Song L, Lan X, Xu Z, Hu Z. Pang H, et al. Nat Metab. 2021 Aug;3(8):1109-1124. doi: 10.1038/s42255-021-00437-0. Epub 2021 Aug 12. Nat Metab. 2021. PMID: 34385701
Zika virus (ZIKV) infection during pregnancy can cause microcephaly in newborns, yet the underlying mechanisms remain largely unexplored. ...
Zika virus (ZIKV) infection during pregnancy can cause microcephaly in newborns, yet the underlying mechanisms remain l
Advancement in the Development of Therapeutics Against Zika Virus Infection.
Li K, Ji Q, Jiang S, Zhang N. Li K, et al. Front Cell Infect Microbiol. 2022 Jul 8;12:946957. doi: 10.3389/fcimb.2022.946957. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35880081 Free PMC article. Review.
Zika virus (ZIKV), a re-emerging arbovirus, causes teratogenic effects on the fetus and normal nerve functions, resulting in harmful autoimmune responses, which call for the development of therapeutics against ZIKV infection. In this review, we introduce the
Zika virus (ZIKV), a re-emerging arbovirus, causes teratogenic effects on the fetus and normal nerve functions, resulting in h
Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2.
Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, Liu Y, Zou G, Lavillete D, Zhao Z, Wang R, Zhu L, Xiao G, Lan K, Li H, Xu K. Xiong R, et al. Protein Cell. 2020 Oct;11(10):723-739. doi: 10.1007/s13238-020-00768-w. Epub 2020 Aug 4. Protein Cell. 2020. PMID: 32754890 Free PMC article.
Herein, we identified two potent inhibitors of human DHODH, S312 and S416, with favorable drug-likeness and pharmacokinetic profiles, which all showed broad-spectrum antiviral effects against various RNA viruses, including influenza A virus, Zika virus, Ebola …
Herein, we identified two potent inhibitors of human DHODH, S312 and S416, with favorable drug-likeness and pharmacokinetic profiles, which …
NSUN2-mediated M5c methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections.
Wang H, Feng J, Zeng C, Liu J, Fu Z, Wang D, Wang Y, Zhang L, Li J, Jiang A, He M, Cao Y, Yan K, Tang H, Guo D, Xu K, Zhou X, Zhou L, Lan K, Zhou Y, Chen Y. Wang H, et al. Emerg Microbes Infect. 2023 Dec;12(1):2178238. doi: 10.1080/22221751.2023.2178238. Emerg Microbes Infect. 2023. PMID: 36748584 Free PMC article.
The highly m(5)C methylated cytosines in IRF3 mRNA were identified, and their mutation enhanced cellular IRF3 mRNA levels. Moreover, infection with Sendai virus (SeV), vesicular stomatitis virus (VSV), herpes simplex virus 1 (HSV-1), or Zika
The highly m(5)C methylated cytosines in IRF3 mRNA were identified, and their mutation enhanced cellular IRF3 mRNA levels. Moreover, infe
Developing human pluripotent stem cell-based cerebral organoids with a controllable microglia ratio for modeling brain development and pathology.
Xu R, Boreland AJ, Li X, Erickson C, Jin M, Atkins C, Pang ZP, Daniels BP, Jiang P. Xu R, et al. Stem Cell Reports. 2021 Aug 10;16(8):1923-1937. doi: 10.1016/j.stemcr.2021.06.011. Epub 2021 Jul 22. Stem Cell Reports. 2021. PMID: 34297942 Free PMC article.
In the organoids, the number of human microglia can be controlled, and microglia exhibit phagocytic activity and synaptic pruning function. Furthermore, human microglia respond to Zika virus infection of the organoids. Our findings establish a new microglia-c …
In the organoids, the number of human microglia can be controlled, and microglia exhibit phagocytic activity and synaptic pruning function. …
Current Progress in the Development of Zika Virus Vaccines.
Zhou K, Li C, Shi W, Hu X, Nandakumar KS, Jiang S, Zhang N. Zhou K, et al. Vaccines (Basel). 2021 Sep 9;9(9):1004. doi: 10.3390/vaccines9091004. Vaccines (Basel). 2021. PMID: 34579241 Free PMC article. Review.
Zika virus (ZIKV) is an arbovirus first discovered in the Americas. ZIKV infection is insidious based on its mild clinical symptoms observed after infection. ...
Zika virus (ZIKV) is an arbovirus first discovered in the Americas. ZIKV infection is insidious based on its mild clini
The in vitro and in vivo antiviral effects of aloperine against Zika virus infection.
Zhou P, Lao Z, Long H, Pan P, Liao F, Zheng W, Li Z, Dai J, Liu H, Jiang Y, Liu X, Wang W, Wu J, Li G. Zhou P, et al. J Med Virol. 2023 Jul;95(7):e28913. doi: 10.1002/jmv.28913. J Med Virol. 2023. PMID: 37409639
Zika virus (ZIKV) infection poses a significant threat to global public health and is associated with microcephaly. There are no approved ZIKV-specific vaccines or drugs for the clinical treatment of the infection. Currently, there are no approved ZIKV
Zika virus (ZIKV) infection poses a significant threat to global public health and is associated with microcephaly. The
Development of Small-Molecule Inhibitors Against Zika Virus Infection.
Wang L, Liang R, Gao Y, Li Y, Deng X, Xiang R, Zhang Y, Ying T, Jiang S, Yu F. Wang L, et al. Front Microbiol. 2019 Dec 6;10:2725. doi: 10.3389/fmicb.2019.02725. eCollection 2019. Front Microbiol. 2019. PMID: 31866959 Free PMC article. Review.
In recent years, the outbreak of infectious disease caused by Zika virus (ZIKV) has posed a major threat to global public health, calling for the development of therapeutics to treat ZIKV disease. Here, we have described the different stages of the ZIKV life cycle a …
In recent years, the outbreak of infectious disease caused by Zika virus (ZIKV) has posed a major threat to global public heal …
Mitophagy Activation Targeting PINK1 Is an Effective Treatment to Inhibit Zika Virus Replication.
Huang Y, Li Q, Kang L, Li B, Ye H, Duan X, Xie H, Jiang M, Li S, Zhu Y, Tan Q, Chen L. Huang Y, et al. ACS Infect Dis. 2023 Jul 14;9(7):1424-1436. doi: 10.1021/acsinfecdis.3c00196. Epub 2023 Jun 10. ACS Infect Dis. 2023. PMID: 37300493
Mitophagy is a selective degradation mechanism that maintains mitochondrial homeostasis by eliminating damaged mitochondria. Many viruses manipulate mitophagy to promote their infection, but its role in Zika virus (ZIKV) is unclear. In this study, we investig …
Mitophagy is a selective degradation mechanism that maintains mitochondrial homeostasis by eliminating damaged mitochondria. Many viruses ma …
114 results