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Year Number of Results
2013 3
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2016 1
2018 1
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2020 5
2021 3
2022 10
2023 12
2024 6

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Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments.
Sheng X, Guan Y, Ma Z, Wu J, Liu H, Qiu C, Vitale S, Miao Z, Seasock MJ, Palmer M, Shin MK, Duffin KL, Pullen SS, Edwards TL, Hellwege JN, Hung AM, Li M, Voight BF, Coffman TM, Brown CD, Susztak K. Sheng X, et al. Among authors: guan y. Nat Genet. 2021 Sep;53(9):1322-1333. doi: 10.1038/s41588-021-00909-9. Epub 2021 Aug 12. Nat Genet. 2021. PMID: 34385711 Free PMC article.
Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing.
Chen L, Zhu B, Ru G, Meng H, Yan Y, Hong M, Zhang D, Luan C, Zhang S, Wu H, Gao H, Bai S, Li C, Ding R, Xue N, Lei Z, Chen Y, Guan Y, Siwko S, Cheng Y, Song G, Wang L, Yi C, Liu M, Li D. Chen L, et al. Among authors: guan y. Nat Biotechnol. 2023 May;41(5):663-672. doi: 10.1038/s41587-022-01532-7. Epub 2022 Nov 10. Nat Biotechnol. 2023. PMID: 36357717
Long-Range Chromatin Interactions in the Kidney.
Guan Y, Liu H, Susztak K. Guan Y, et al. J Am Soc Nephrol. 2019 Mar;30(3):367-369. doi: 10.1681/ASN.2019010044. Epub 2019 Feb 13. J Am Soc Nephrol. 2019. PMID: 30760498 Free PMC article. No abstract available.
Engineering APOBEC3A deaminase for highly accurate and efficient base editing.
Yang L, Huo Y, Wang M, Zhang D, Zhang T, Wu H, Rao X, Meng H, Yin S, Mei J, Zhang D, Chen X, Lv J, Liu M, Cheng Y, Guan Y, Feng B, Song G, Yi C, Liu M, Zeng F, Wang L, Li D. Yang L, et al. Among authors: guan y. Nat Chem Biol. 2024 Mar 29. doi: 10.1038/s41589-024-01595-4. Online ahead of print. Nat Chem Biol. 2024. PMID: 38553609
44 results