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yangqi ai
(2 results)?
Conversion Discriminative Analysis on Mild Cognitive Impairment Using Multiple Cortical Features from MR Images.
Front Aging Neurosci. 2017 May 18;9:146. doi: 10.3389/fnagi.2017.00146. eCollection 2017.
Front Aging Neurosci. 2017.
PMID: 28572766
Free PMC article.
Modulating the interaction between CDK2 and cyclin A with a quinoline-based inhibitor.
Deng Y, Shipps GW Jr, Zhao L, Siddiqui MA, Popovici-Muller J, Curran PJ, Duca JS, Hruza AW, Fischmann TO, Madison VS, Zhang R, McNemar CW, Mayhood TW, Syto R, Annis A, Kirschmeier P, Lees EM, Parry DA, Windsor WT.
Deng Y, et al.
Bioorg Med Chem Lett. 2014 Jan 1;24(1):199-203. doi: 10.1016/j.bmcl.2013.11.041. Epub 2013 Nov 23.
Bioorg Med Chem Lett. 2014.
PMID: 24332088
A new class of quinoline-based kinase inhibitors has been discovered that both disrupt cyclin dependent 2 (CDK2) interaction with its cyclin A subunit and act as ATP competitive inhibitors. ...
A new class of quinoline-based kinase inhibitors has been discovered that both disrupt cyclin dependent 2 (CDK2) interaction with its …
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Discovery of liver-targeted inhibitors of stearoyl-CoA desaturase (SCD1).
Deng Y, Yang Z, Shipps GW Jr, Lo SM, West R, Hwa J, Zheng S, Farley C, Lachowicz J, van Heek M, Bass AS, Sinha DP, Mahon CR, Cartwright ME.
Deng Y, et al.
Bioorg Med Chem Lett. 2013 Feb 1;23(3):791-6. doi: 10.1016/j.bmcl.2012.11.075. Epub 2012 Dec 5.
Bioorg Med Chem Lett. 2013.
PMID: 23265904
Inhibitors based on a benzo-fused spirocyclic oxazepine scaffold were discovered for stearoyl-coenzyme A (CoA) desaturase 1 (SCD1) and subsequently optimized to potent compounds with favorable pharmacokinetic profiles and in vivo efficacy in reducing the desaturation index …
Inhibitors based on a benzo-fused spirocyclic oxazepine scaffold were discovered for stearoyl-coenzyme A (CoA) desaturase 1 (SCD1) an …
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Discovery of 4H-pyrazolo[1,5-a]pyrimidin-7-ones as potent inhibitors of hepatitis C virus polymerase.
Deng Y, Shipps GW Jr, Wang T, Popovici-Muller J, Rosner KE, Siddiqui MA, Duca J, Cooper AB, Cable M.
Deng Y, et al.
Bioorg Med Chem Lett. 2009 Sep 15;19(18):5363-7. doi: 10.1016/j.bmcl.2009.07.124. Epub 2009 Aug 6.
Bioorg Med Chem Lett. 2009.
PMID: 19682898
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