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Page 1
Chemical architecture and applications of nucleic acid derivatives containing 1,2,3-triazole functionalities synthesized via click chemistry.
Molecules. 2012 Oct 26;17(11):12665-703. doi: 10.3390/molecules171112665.
Molecules. 2012.
PMID: 23103533
Free PMC article.
Review.
Synthesis of triazole-nucleoside phosphoramidites and their use in solid-phase oligonucleotide synthesis.
Peel BJ, Efthymiou TC, Desaulniers JP.
Peel BJ, et al. Among authors: efthymiou tc.
Curr Protoc Nucleic Acid Chem. 2014 Dec 19;55:4.57.1-38. doi: 10.1002/0471142700.nc0457s55.
Curr Protoc Nucleic Acid Chem. 2014.
PMID: 25631534
Review.
Item in Clipboard
Chimeric XNA: An Unconventional Design for Orthogonal Informational Systems.
Efthymiou T, Gavette J, Stoop M, De Riccardis F, Froeyen M, Herdewijn P, Krishnamurthy R.
Efthymiou T, et al.
Chemistry. 2018 Sep 3;24(49):12811-12819. doi: 10.1002/chem.201802287. Epub 2018 Aug 10.
Chemistry. 2018.
PMID: 29901248
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Inhaled delivery of a lipid nanoparticle encapsulated messenger RNA encoding a ciliary protein for the treatment of primary ciliary dyskinesia.
Woo CJ, Allawzi A, Clark N, Kaushal N, Efthymiou T, Thamsen M, Nguyen J, Wooster R, Sullivan JC.
Woo CJ, et al. Among authors: efthymiou t.
Pulm Pharmacol Ther. 2022 Aug;75:102134. doi: 10.1016/j.pupt.2022.102134. Epub 2022 May 22.
Pulm Pharmacol Ther. 2022.
PMID: 35613658
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Evaluation of siRNAs that contain internal variable-length spacer linkages.
Efthymiou TC, Peel B, Huynh V, Desaulniers JP.
Efthymiou TC, et al.
Bioorg Med Chem Lett. 2012 Sep 1;22(17):5590-4. doi: 10.1016/j.bmcl.2012.07.006. Epub 2012 Jul 16.
Bioorg Med Chem Lett. 2012.
PMID: 22850216
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Efficient synthesis and cell-based silencing activity of siRNAS that contain triazole backbone linkages.
Efthymiou TC, Huynh V, Oentoro J, Peel B, Desaulniers JP.
Efthymiou TC, et al.
Bioorg Med Chem Lett. 2012 Feb 15;22(4):1722-6. doi: 10.1016/j.bmcl.2011.12.104. Epub 2011 Dec 30.
Bioorg Med Chem Lett. 2012.
PMID: 22260772
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Microwave-assisted phosphitylation of DNA and RNA nucleosides and their analogs.
Efthymiou T, Krishnamurthy R.
Efthymiou T, et al.
Curr Protoc Nucleic Acid Chem. 2015 Mar 9;60:2.19.1-2.19.20. doi: 10.1002/0471142700.nc0219s60.
Curr Protoc Nucleic Acid Chem. 2015.
PMID: 25754891
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