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Page 1
Macrocyclic Carbon-Linked Pyrazoles As Novel Inhibitors of MCL-1.
ACS Med Chem Lett. 2023 Jul 3;14(7):955-961. doi: 10.1021/acsmedchemlett.3c00141. eCollection 2023 Jul 13.
ACS Med Chem Lett. 2023.
PMID: 37465311
Expedient Access to Cyanated N-Heterocycles by Direct Flow-Electrochemical C(sp2 )-H Activation.
Carvalho MA, Demin S, Martinez-Lamenca C, Romanov-Michailidis F, Lam K, Rombouts F, Lecomte M.
Carvalho MA, et al. Among authors: demin s.
Chemistry. 2022 Jan 3;28(1):e202103384. doi: 10.1002/chem.202103384. Epub 2021 Nov 5.
Chemistry. 2022.
PMID: 34658083
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Discovery of 3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one (JNJ-53718678), a Potent and Orally Bioavailable Fusion Inhibitor of Respiratory Syncytial Virus.
Vendeville S, Tahri A, Hu L, Demin S, Cooymans L, Vos A, Kwanten L, Van den Berg J, Battles MB, McLellan JS, Koul A, Raboisson P, Roymans D, Jonckers THM.
Vendeville S, et al. Among authors: demin s.
J Med Chem. 2020 Aug 13;63(15):8046-8058. doi: 10.1021/acs.jmedchem.0c00226. Epub 2020 Jun 15.
J Med Chem. 2020.
PMID: 32407115
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Novel Pyrimidine Toll-like Receptor 7 and 8 Dual Agonists to Treat Hepatitis B Virus.
McGowan D, Herschke F, Pauwels F, Stoops B, Last S, Pieters S, Scholliers A, Thoné T, Van Schoubroeck B, De Pooter D, Mostmans W, Khamlichi MD, Embrechts W, Dhuyvetter D, Smyej I, Arnoult E, Demin S, Borghys H, Fanning G, Vlach J, Raboisson P.
McGowan D, et al. Among authors: demin s.
J Med Chem. 2016 Sep 8;59(17):7936-49. doi: 10.1021/acs.jmedchem.6b00747. Epub 2016 Aug 23.
J Med Chem. 2016.
PMID: 27513093
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Asymmetric synthesis of (7aS)-7a-methyl-4,5,7,7a-tetrahydro-1H-indene-2,6-dione and useful derivatives thereof.
Demin S, Van Haver D, De Clercq PJ.
Demin S, et al.
Molecules. 2006 Sep 18;11(9):707-13. doi: 10.3390/11090707.
Molecules. 2006.
PMID: 17971745
Free PMC article.
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Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: cis-perhydrindane CE-ring analogues.
Demin S, Van Haver D, Vandewalle M, De Clercq PJ, Bouillon R, Verstuyf A.
Demin S, et al.
Bioorg Med Chem Lett. 2004 Aug 2;14(15):3885-8. doi: 10.1016/j.bmcl.2004.05.067.
Bioorg Med Chem Lett. 2004.
PMID: 15225690
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