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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1938 1
1978 1
1979 1
1982 1
1983 1
1984 3
1987 4
1988 1
1989 2
1990 1
1991 2
1992 4
1993 2
1994 5
1995 4
1996 4
1997 4
1998 1
1999 8
2000 5
2001 7
2002 4
2003 3
2004 4
2005 4
2006 8
2007 5
2008 7
2009 7
2010 9
2011 2
2012 10
2013 7
2014 9
2015 15
2016 11
2017 4
2018 5
2019 7
2020 3
2021 10
2022 5
2023 8
2024 3

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203 results

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Page 1
Ustekinumab as Induction and Maintenance Therapy for Crohn's Disease.
Feagan BG, Sandborn WJ, Gasink C, Jacobstein D, Lang Y, Friedman JR, Blank MA, Johanns J, Gao LL, Miao Y, Adedokun OJ, Sands BE, Hanauer SB, Vermeire S, Targan S, Ghosh S, de Villiers WJ, Colombel JF, Tulassay Z, Seidler U, Salzberg BA, Desreumaux P, Lee SD, Loftus EV Jr, Dieleman LA, Katz S, Rutgeerts P; UNITI–IM-UNITI Study Group. Feagan BG, et al. N Engl J Med. 2016 Nov 17;375(20):1946-1960. doi: 10.1056/NEJMoa1602773. N Engl J Med. 2016. PMID: 27959607 Free article. Clinical Trial.
The primary end point for the induction trials was a clinical response at week 6 (defined as a decrease from baseline in the Crohn's Disease Activity Index [CDAI] score of 100 points or a CDAI score <150). ...CONCLUSIONS: Among patients with moderately to severely activ …
The primary end point for the induction trials was a clinical response at week 6 (defined as a decrease from baseline in the Crohn's …
Pre-encoded responsiveness to type I interferon in the peripheral immune system defines outcome of PD1 blockade therapy.
Boukhaled GM, Gadalla R, Elsaesser HJ, Abd-Rabbo D, Quevedo R, Yang SYC, Guo M, Wang BX, Noamani B, Gray D, Lau SCM, Taylor K, Aung K, Spreafico A, Hansen AR, Saibil SD, Hirano N, Guidos C, Pugh TJ, McGaha TL, Ohashi PS, Sacher AG, Butler MO, Brooks DG. Boukhaled GM, et al. Nat Immunol. 2022 Aug;23(8):1273-1283. doi: 10.1038/s41590-022-01262-7. Epub 2022 Jul 14. Nat Immunol. 2022. PMID: 35835962
Cryo-EM in molecular and cellular biology.
Saibil HR. Saibil HR. Mol Cell. 2022 Jan 20;82(2):274-284. doi: 10.1016/j.molcel.2021.12.016. Mol Cell. 2022. PMID: 35063096 Free article. Review.
Structural Analysis of Protein Complexes by Cryo-Electron Microscopy.
Ignatiou A, Macé K, Redzej A, Costa TRD, Waksman G, Orlova EV. Ignatiou A, et al. Methods Mol Biol. 2024;2715:431-470. doi: 10.1007/978-1-0716-3445-5_27. Methods Mol Biol. 2024. PMID: 37930544 Review.
During the last decade, structural cryo-EM has become broadly used for the analysis of the bio-complexes that comprise multiple components and are not amenable to crystallization (Lyumkis, J Biol Chem 294:5181-5197, 2019; Orlova and Saibil, Methods Enzymol 482:321-341, 201 …
During the last decade, structural cryo-EM has become broadly used for the analysis of the bio-complexes that comprise multiple components a …
Targeting T cell activation in immuno-oncology.
Saibil SD, Ohashi PS. Saibil SD, et al. Curr Oncol. 2020 Apr;27(Suppl 2):S98-S105. doi: 10.3747/co.27.5285. Epub 2020 Apr 1. Curr Oncol. 2020. PMID: 32368179 Free PMC article. Review.
A structural basis for prion strain diversity.
Manka SW, Wenborn A, Betts J, Joiner S, Saibil HR, Collinge J, Wadsworth JDF. Manka SW, et al. Nat Chem Biol. 2023 May;19(5):607-613. doi: 10.1038/s41589-022-01229-7. Epub 2023 Jan 16. Nat Chem Biol. 2023. PMID: 36646960 Free PMC article.
Cryo-EM of amyloid fibrils and cellular aggregates.
Fitzpatrick AW, Saibil HR. Fitzpatrick AW, et al. Curr Opin Struct Biol. 2019 Oct;58:34-42. doi: 10.1016/j.sbi.2019.05.003. Epub 2019 Jun 12. Curr Opin Struct Biol. 2019. PMID: 31200186 Free PMC article. Review.
Chaperonins.
Ranson NA, White HE, Saibil HR. Ranson NA, et al. Biochem J. 1998 Jul 15;333 ( Pt 2)(Pt 2):233-42. doi: 10.1042/bj3330233. Biochem J. 1998. PMID: 9657960 Free PMC article. Review.
Inflammatory pouch disease: The spectrum of pouchitis.
Zezos P, Saibil F. Zezos P, et al. World J Gastroenterol. 2015 Aug 7;21(29):8739-52. doi: 10.3748/wjg.v21.i29.8739. World J Gastroenterol. 2015. PMID: 26269664 Free PMC article. Review.
IPAA can be a treatment option for selected patients with Crohn's colitis without perianal and/or small bowel disease. The term "pouchitis" refers to nonspecific inflammation of the pouch and is a common complication in patients with IPAA; it occurs more often in UC patien …
IPAA can be a treatment option for selected patients with Crohn's colitis without perianal and/or small bowel disease. The term "pouc …
203 results