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Year Number of Results
1984 1
1986 1
1992 1
1995 1
1997 1
1999 1
2002 2
2003 3
2004 2
2005 4
2006 7
2007 2
2008 3
2009 7
2010 1
2011 5
2012 1
2013 2
2014 3
2015 2
2016 2
2017 1
2018 1
2019 1
2020 2
2021 10
2022 6
2023 5
2024 0

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67 results

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Page 1
Identification of MRTX1133, a Noncovalent, Potent, and Selective KRASG12D Inhibitor.
Wang X, Allen S, Blake JF, Bowcut V, Briere DM, Calinisan A, Dahlke JR, Fell JB, Fischer JP, Gunn RJ, Hallin J, Laguer J, Lawson JD, Medwid J, Newhouse B, Nguyen P, O'Leary JM, Olson P, Pajk S, Rahbaek L, Rodriguez M, Smith CR, Tang TP, Thomas NC, Vanderpool D, Vigers GP, Christensen JG, Marx MA. Wang X, et al. J Med Chem. 2022 Feb 24;65(4):3123-3133. doi: 10.1021/acs.jmedchem.1c01688. Epub 2021 Dec 10. J Med Chem. 2022. PMID: 34889605 Free article.
Comparison of treatment strategies for neonates with tetralogy of Fallot and pulmonary atresia.
Meadows JJ, Bauser-Heaton H, Petit CJ, Goldstein BH, Qureshi AM, McCracken CE, Kelleman MS, Nicholson GT, Law MA, Zampi JD, Shahanavaz S, Chai PJ, Romano JC, Batlivala SP, Maskatia SA, Asztalos IB, Eilers L, Kamsheh AM, Healan SJ, Smith JD, Ligon RA, Dailey-Schwartz A, Pettus JA, Pajk AL, Glatz AC, Mascio CE. Meadows JJ, et al. J Thorac Cardiovasc Surg. 2023 Sep;166(3):916-925.e6. doi: 10.1016/j.jtcvs.2023.01.008. Epub 2023 Jan 14. J Thorac Cardiovasc Surg. 2023. PMID: 36828672
Mechanistic Studies Yield Improved Protocols for Base-Catalyzed Anti-Markovnikov Alcohol Addition Reactions.
Luo C, Alegre-Requena JV, Sujansky SJ, Pajk SP, Gallegos LC, Paton RS, Bandar JS. Luo C, et al. J Am Chem Soc. 2022 Jun 8;144(22):9586-9596. doi: 10.1021/jacs.1c13397. Epub 2022 May 23. J Am Chem Soc. 2022. PMID: 35605253
These observations led to an unexpected solution to a thermodynamically challenging reaction: use of less alcohol enables faster addition, which in turn allows for lower reaction temperatures to counteract Le Chatelier's principle. Thus, our original method has been improv …
These observations led to an unexpected solution to a thermodynamically challenging reaction: use of less alcohol enables faster addition, w …
COVID19 Impairs Cardiac Function via Endothelial H19 and IL6 Signaling.
Juni RP, Phelp PG, Bink DI, Kremer V, van Bergen AS, Espinosa Gonzalez P, Rombouts KB, Harber KJ, Heister DAF, Yeung KK, Van den Bossche J, Kuster DWD; Amsterdam UMC COVID-19 Biobank Study Group; Krijnen PAJ, Niessen HWM, Boon RA. Juni RP, et al. Circ Res. 2023 Mar 3;132(5):648-651. doi: 10.1161/CIRCRESAHA.122.322166. Epub 2023 Feb 14. Circ Res. 2023. PMID: 36786206 Free PMC article. No abstract available.
Pulmonary Artery Hypoplasia in Neonates With Tetralogy of Fallot.
Petit CJ, Glatz AC, Goldstone AB, Law MA, Romano JC, Maskatia SA, Chai PJ, Zampi JD, Meadows JJ, Nicholson GT, Shahanavaz S, Qureshi AM, McCracken CE, Mascio CE, Batlivala SP, Asztalos IB, Healan SJ, Smith JD, Pettus JA, Beshish A, Raulston JEB, Hock KM, Pajk AL, Goldstein BH. Petit CJ, et al. J Am Coll Cardiol. 2023 Aug 15;82(7):615-627. doi: 10.1016/j.jacc.2023.05.051. J Am Coll Cardiol. 2023. PMID: 37558375
Palliation Strategy to Achieve Complete Repair in Symptomatic Neonates with Tetralogy of Fallot.
Law MA, Glatz AC, Romano JC, Chai PJ, Mascio CE, Petit CJ, McCracken CE, Kelleman MS, Nicholson GT, Meadows JJ, Zampi JD, Shahanavaz S, Batlivala SP, Pettus J, Pajk AL, Hock KM, Goldstein BH, Qureshi AM; Congenital Cardiac Research Collaborative (CCRC) Investigators. Law MA, et al. Pediatr Cardiol. 2022 Oct;43(7):1587-1598. doi: 10.1007/s00246-022-02886-0. Epub 2022 Apr 5. Pediatr Cardiol. 2022. PMID: 35381860
Cutaneous Microvascular Blood Flow and Reactivity in Hypoxia.
Treml B, Kleinsasser A, Stadlbauer KH, Steiner I, Pajk W, Pilch M, Burtscher M, Knotzer H. Treml B, et al. Front Physiol. 2018 Mar 6;9:160. doi: 10.3389/fphys.2018.00160. eCollection 2018. Front Physiol. 2018. PMID: 29559919 Free PMC article.
Short-term acclimatization had no effect on microcirculatory blood flow. When testing for a hyperemic response of the skin's microcirculation we found a diminished signal in hypoxia, indicative for a compromised auto-regulative circulatory capacity. ...
Short-term acclimatization had no effect on microcirculatory blood flow. When testing for a hyperemic response of the skin's microcir …
67 results