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Astrocytes Differentiated from LRRK2-I1371V Parkinson's-Disease-Induced Pluripotent Stem Cells Exhibit Similar Yield but Cell-Intrinsic Dysfunction in Glutamate Uptake and Metabolism, ATP Generation, and Nrf2-Mediated Glutathione Machinery.
Cells. 2023 Jun 8;12(12):1592. doi: 10.3390/cells12121592.
Cells. 2023.
PMID: 37371062
Free PMC article.
Presence of Extracellular Alpha-Synuclein Aggregates Trigger Astrocytic Degeneration Through Enhanced Membrane Rigidity and Deregulation of Store-Operated Calcium Entry (SOCE) into the Endoplasmic Reticulum.
Raj A, Banerjee R, Santhoshkumar R, Sagar C, Datta I.
Raj A, et al. Among authors: banerjee r.
Mol Neurobiol. 2023 Sep;60(9):5309-5329. doi: 10.1007/s12035-023-03400-0. Epub 2023 Jun 8.
Mol Neurobiol. 2023.
PMID: 37289385
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Generation of induced pluripotent stem cells (NIMHi015-A) from a Parkinson's Disease patient harbouring a homozygous Exon 3 deletion in the PRKN gene.
Banerjee R, Ghanty R, Jagtap S, Holla V, Kamble N, Yadav R, Pal PK, Datta I.
Banerjee R, et al.
Stem Cell Res. 2024 May 9;77:103440. doi: 10.1016/j.scr.2024.103440. Online ahead of print.
Stem Cell Res. 2024.
PMID: 38739971
Free article.
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