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christopher e. Boyle
(2 results)?
Duocarmycin SA, a potent antitumor antibiotic, sensitizes glioblastoma cells to proton radiation.
Bioorg Med Chem Lett. 2018 Sep 1;28(16):2688-2692. doi: 10.1016/j.bmcl.2018.04.008. Epub 2018 Apr 4.
Bioorg Med Chem Lett. 2018.
PMID: 29650288
Free PMC article.
Synthesis and evaluation of duocarmycin SA analogs incorporating the methyl 1,2,8,8a-tetrahydrocyclopropa[c]imidazolo[4,5-e]indol-4-one-6-carboxylate (CImI) alkylation subunit.
Chanda PB, Boyle KE, Brody DM, Shukla V, Boger DL.
Chanda PB, et al. Among authors: boyle ke.
Bioorg Med Chem. 2016 Oct 15;24(20):4779-4786. doi: 10.1016/j.bmc.2016.04.050. Epub 2016 Apr 26.
Bioorg Med Chem. 2016.
PMID: 27221071
Free PMC article.
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Synthesis and evaluation of duocarmycin SA analogs incorporating the methyl 1,2,8,8a-tetrahydrocyclopropa[c]oxazolo[2,3-e]indol-4-one-6-carboxylate (COI) alkylation subunit.
Boyle KE, MacMillan KS, Ellis DA, Lajiness JP, Robertson WM, Boger DL.
Boyle KE, et al.
Bioorg Med Chem Lett. 2010 Mar 15;20(6):1854-7. doi: 10.1016/j.bmcl.2010.01.145. Epub 2010 Feb 2.
Bioorg Med Chem Lett. 2010.
PMID: 20171886
Free PMC article.
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Duocarmycin SA Reduces Proliferation and Increases Apoptosis in Acute Myeloid Leukemia Cells In Vitro.
Chen WA, Williams TG, So L, Drew N, Fang J, Ochoa P, Nguyen N, Jawhar Y, Otiji J, Duerksen-Hughes PJ, Reeves ME, Casiano CA, Jin H, Dovat S, Yang J, Boyle KE, Francis-Boyle OL.
Chen WA, et al. Among authors: boyle ke.
Int J Mol Sci. 2024 Apr 14;25(8):4342. doi: 10.3390/ijms25084342.
Int J Mol Sci. 2024.
PMID: 38673926
Free PMC article.
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Discovery of HIV fusion inhibitors targeting gp41 using a comprehensive α-helix mimetic library.
Whitby LR, Boyle KE, Cai L, Yu X, Gochin M, Boger DL.
Whitby LR, et al. Among authors: boyle ke.
Bioorg Med Chem Lett. 2012 Apr 15;22(8):2861-5. doi: 10.1016/j.bmcl.2012.02.062. Epub 2012 Mar 3.
Bioorg Med Chem Lett. 2012.
PMID: 22424973
Free PMC article.
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Novel, highly potent, selective 5-HT2A/D2 receptor antagonists as potential atypical antipsychotics.
Lee T, Robichaud AJ, Boyle KE, Lu Y, Robertson DW, Miller KJ, Fitzgerald LW, McElroy JF, Largent BL.
Lee T, et al. Among authors: boyle ke.
Bioorg Med Chem Lett. 2003 Feb 24;13(4):767-70. doi: 10.1016/s0960-894x(02)01028-4.
Bioorg Med Chem Lett. 2003.
PMID: 12639577
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