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Page 1
Targeting the ACOD1-itaconate axis stabilizes atherosclerotic plaques.
Harber KJ, Neele AE, van Roomen CP, Gijbels MJ, Beckers L, Toom MD, Schomakers BV, Heister DA, Willemsen L, Griffith GR, de Goede KE, van Dierendonck XA, Reiche ME, Poli A, L-H Mogensen F, Michelucci A, Verberk SG, de Vries H, van Weeghel M, Van den Bossche J, de Winther MP. Harber KJ, et al. Redox Biol. 2024 Apr;70:103054. doi: 10.1016/j.redox.2024.103054. Epub 2024 Jan 22. Redox Biol. 2024. PMID: 38309122 Free PMC article.
Let's Enter the Wonderful World of Immunometabolites.
de Goede KE, Harber KJ, Van den Bossche J. de Goede KE, et al. Among authors: harber kj. Trends Endocrinol Metab. 2019 Jun;30(6):329-331. doi: 10.1016/j.tem.2019.03.004. Epub 2019 May 3. Trends Endocrinol Metab. 2019. PMID: 31060882
d-2-Hydroxyglutarate is an anti-inflammatory immunometabolite that accumulates in macrophages after TLR4 activation.
de Goede KE, Harber KJ, Gorki FS, Verberk SGS, Groh LA, Keuning ED, Struys EA, van Weeghel M, Haschemi A, de Winther MPJ, van Dierendonck XAMH, Van den Bossche J. de Goede KE, et al. Among authors: harber kj. Biochim Biophys Acta Mol Basis Dis. 2022 Sep 1;1868(9):166427. doi: 10.1016/j.bbadis.2022.166427. Epub 2022 May 6. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35526742 Free article.
COVID19 Impairs Cardiac Function via Endothelial H19 and IL6 Signaling.
Juni RP, Phelp PG, Bink DI, Kremer V, van Bergen AS, Espinosa Gonzalez P, Rombouts KB, Harber KJ, Heister DAF, Yeung KK, Van den Bossche J, Kuster DWD; Amsterdam UMC COVID-19 Biobank Study Group; Krijnen PAJ, Niessen HWM, Boon RA. Juni RP, et al. Among authors: harber kj. Circ Res. 2023 Mar 3;132(5):648-651. doi: 10.1161/CIRCRESAHA.122.322166. Epub 2023 Feb 14. Circ Res. 2023. PMID: 36786206 Free PMC article. No abstract available.
Myeloid ATP Citrate Lyase Regulates Macrophage Inflammatory Responses In Vitro Without Altering Inflammatory Disease Outcomes.
Verberk SGS, van der Zande HJP, Baardman J, de Goede KE, Harber KJ, Keuning ED, Lambooij JM, Otto F, Zawistowska-Deniziak A, de Vries HE, de Winther MPJ, Guigas B, Van den Bossche J. Verberk SGS, et al. Among authors: harber kj. Front Immunol. 2021 Apr 26;12:669920. doi: 10.3389/fimmu.2021.669920. eCollection 2021. Front Immunol. 2021. PMID: 33981315 Free PMC article.
An HLA-A*11:01-Binding Neoantigen from Mutated NPM1 as Target for TCR Gene Therapy in AML.
van der Lee DI, Koutsoumpli G, Reijmers RM, Honders MW, de Jong RCM, Remst DFG, Wachsmann TLA, Hagedoorn RS, Franken KLMC, Kester MGD, Harber KJ, Roelofsen LM, Schouten AM, Mulder A, Drijfhout JW, Veelken H, van Veelen PA, Heemskerk MHM, Falkenburg JHF, Griffioen M. van der Lee DI, et al. Among authors: harber kj. Cancers (Basel). 2021 Oct 27;13(21):5390. doi: 10.3390/cancers13215390. Cancers (Basel). 2021. PMID: 34771556 Free PMC article.