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In vitro microbiological evaluation of 1,1'-(5,5'-(1,4-phenylene)bis(3-aryl-1H-pyrazole-5,1-(4H,5H)-diyl))diethanones, novel bisacetylated pyrazoles.
Kanagarajan V, Ezhilarasi MR, Gopalakrishnan M. Kanagarajan V, et al. Org Med Chem Lett. 2011 Sep 20;1(1):8. doi: 10.1186/2191-2858-1-8. Org Med Chem Lett. 2011. PMID: 22373408 Free PMC article.
Compounds 7 against Micrococcus luteus, 8 against beta-Heamolytic streptococcus, M. luteus, Klebsiella pneumonia, Microsporum gypseum, 9 against Staphylococcus aureus, Shigella flexneri, Vibreo cholerae, Pseudomonas aeruginosa, Aspergillus flavus, Mucor indicus, 10 against Salmon …
Compounds 7 against Micrococcus luteus, 8 against beta-Heamolytic streptococcus, M. luteus, Klebsiella pneumonia, Microsporum gypseum, 9 aga …
4-(4-morpholinophenyl)-6-arylpyrimidin-2-amines: synthesis, spectral analysis, and in vitro microbiological evaluation.
Thanusu J, Kanagarajan V, Gopalakrishnan M. Thanusu J, et al. J Enzyme Inhib Med Chem. 2010 Jun;25(3):347-53. doi: 10.3109/14756360903179468. J Enzyme Inhib Med Chem. 2010. PMID: 19874135
Compounds 4-(4-fluorophenyl)-6-(4-morpholinophenyl)pyrimidin-2-amine 24 and 25 (against beta-hemolytic Streptococcus) and compound 28 (against S. felxneri) showed pronounced activity. Compounds 26 and 28 (against K. pneumoniae) and compounds 24, 25, and 28 (against P. aeru …
Compounds 4-(4-fluorophenyl)-6-(4-morpholinophenyl)pyrimidin-2-amine 24 and 25 (against beta-hemolytic Streptococcus) and compound 28 (again …
Functional expression and characterization of sesquiterpene synthases from Artemisia annua L. using transient expression system in Nicotiana benthamiana.
Kanagarajan S, Muthusamy S, Gliszczyńska A, Lundgren A, Brodelius PE. Kanagarajan S, et al. Plant Cell Rep. 2012 Jul;31(7):1309-19. doi: 10.1007/s00299-012-1250-z. Epub 2012 May 8. Plant Cell Rep. 2012. PMID: 22565787
The purified enzymes exhibited the specific activity of 0.002 and 0.01 mumol min-1 mg-1 protein for ADS and ECS, respectively. The apparent k(cat) values were 2.1 10-3 s-1 and 11 10-3 s-1 for ADS and ECS, respectively. ...
The purified enzymes exhibited the specific activity of 0.002 and 0.01 mumol min-1 mg-1 protein for ADS and ECS, respectively. The apparent …
Activated fly ash catalyzed facile synthesis of novel spiro imidazolidine derivatives as potential antibacterial and antifungal agents.
Kanagarajan V, Thanusu J, Gopalakrishnan M. Kanagarajan V, et al. J Enzyme Inhib Med Chem. 2011 Apr;26(2):280-7. doi: 10.3109/14756366.2010.503611. Epub 2010 Aug 5. J Enzyme Inhib Med Chem. 2011. PMID: 20687790
Structure-activity relationship results revealed that compounds 22, 23 against P.aeruginosa, 24 against S.aureus, 24, 25 against K.pneumonia, 27 against S.aureus, beta-H.streptococcus, 29 against M.luteus, K.pneumonia, 29, 30 against P.vulgaris exhibited excellent a …
Structure-activity relationship results revealed that compounds 22, 23 against P.aeruginosa, 24 against S.aureus, 24, 25 against K.pn …