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An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function.
Cuesta-Hernández HN, Contreras J, Soriano-Maldonado P, Sánchez-Wandelmer J, Yeung W, Martín-Hurtado A, Muñoz IG, Kannan N, Llimargas M, Muñoz J, Plaza-Menacho I. Cuesta-Hernández HN, et al. Among authors: contreras j. Nat Commun. 2023 Oct 17;14(1):6548. doi: 10.1038/s41467-023-41890-7. Nat Commun. 2023. PMID: 37848415 Free PMC article.
An UPF3-based nonsense-mediated decay in Paramecium.
Contreras J, Begley V, Macias S, Villalobo E. Contreras J, et al. Res Microbiol. 2014 Dec;165(10):841-6. doi: 10.1016/j.resmic.2014.10.008. Epub 2014 Oct 22. Res Microbiol. 2014. PMID: 25463387 Free article.
Association of snR190 snoRNA chaperone with early pre-60S particles is regulated by the RNA helicase Dbp7 in yeast.
Jaafar M, Contreras J, Dominique C, Martín-Villanueva S, Capeyrou R, Vitali P, Rodríguez-Galán O, Velasco C, Humbert O, Watkins NJ, Villalobo E, Bohnsack KE, Bohnsack MT, Henry Y, Merhi RA, de la Cruz J, Henras AK. Jaafar M, et al. Among authors: contreras j. Nat Commun. 2021 Oct 22;12(1):6153. doi: 10.1038/s41467-021-26207-w. Nat Commun. 2021. PMID: 34686656 Free PMC article.
PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin.
Lucena-Agell D, Guillén MJ, Matesanz R, Álvarez-Bernad B, Hortigüela R, Avilés P, Martínez-Díez M, Santamaría-Núñez G, Contreras J, Plaza-Menacho I, Giménez-Abián JF, Oliva MA, Cuevas C, Díaz JF. Lucena-Agell D, et al. Among authors: contreras j. J Med Chem. 2024 Feb 22;67(4):2619-2630. doi: 10.1021/acs.jmedchem.3c01775. Epub 2024 Jan 31. J Med Chem. 2024. PMID: 38294341 Free PMC article.