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Year Number of Results
2008 1
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2020 4
2021 3
2023 5
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Page 1
A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer's disease.
Haque R, Watson CM, Liu J, Carter EK, Duong DM, Lah JJ, Wingo AP, Roberts BR, Johnson ECB, Saykin AJ, Shaw LM, Seyfried NT, Wingo TS, Levey AI. Haque R, et al. Sci Transl Med. 2023 Sep 6;15(712):eadg4122. doi: 10.1126/scitranslmed.adg4122. Epub 2023 Sep 6. Sci Transl Med. 2023. PMID: 37672565 Free PMC article.
On the basis of our prior work integrating cerebrospinal fluid (CSF) and brain proteome networks, we developed a reliable and high-throughput mass spectrometry-selected reaction monitoring assay that targets 48 key proteins altered in CSF. ...
On the basis of our prior work integrating cerebrospinal fluid (CSF) and brain proteome networks, we developed a reliable and high- …
A bioinformatics potpourri.
Schönbach C, Li J, Ma L, Horton P, Sjaugi MF, Ranganathan S. Schönbach C, et al. BMC Genomics. 2018 Jan 19;19(Suppl 1):920. doi: 10.1186/s12864-017-4326-x. BMC Genomics. 2018. PMID: 29363432 Free PMC article.
Fifty-seven articles comprising a topic assortment of algorithms, biomolecular networks, cancer and disease informatics, drug-target interactions and drug efficacy, gene regulation and expression, imaging, immunoinformatics, metagenomics, next generation sequencing for genomics a …
Fifty-seven articles comprising a topic assortment of algorithms, biomolecular networks, cancer and disease informatics, drug-target interac …
Update on bladder cancer molecular subtypes.
Fong MHY, Feng M, McConkey DJ, Choi W. Fong MHY, et al. Transl Androl Urol. 2020 Dec;9(6):2881-2889. doi: 10.21037/tau-2019-mibc-12. Transl Androl Urol. 2020. PMID: 33457262 Free PMC article. Review.
In 2014, there was a burst of studies on the molecular subtypes of bladder cancer in the published literature that was made possible by the advances in high-throughput technologies. Based on gene expression profiling, the major molecular classification subdivisions …
In 2014, there was a burst of studies on the molecular subtypes of bladder cancer in the published literature that was made possible by the …
Systems biology approaches towards predictive microbial ecology.
Otwell AE, López García de Lomana A, Gibbons SM, Orellana MV, Baliga NS. Otwell AE, et al. Environ Microbiol. 2018 Dec;20(12):4197-4209. doi: 10.1111/1462-2920.14378. Epub 2018 Oct 19. Environ Microbiol. 2018. PMID: 30106224
In this perspective, we emphasize the importance of pursuing a multiscale, systems approach to iteratively link ecological processes measured in the field to testable hypotheses that drive high-throughput laboratory experimentation. Mechanistic understanding of micr …
In this perspective, we emphasize the importance of pursuing a multiscale, systems approach to iteratively link ecological processes measure …
Recent developments in the management of congenital cataract.
Bremond-Gignac D, Daruich A, Robert MP, Valleix S. Bremond-Gignac D, et al. Ann Transl Med. 2020 Nov;8(22):1545. doi: 10.21037/atm-20-3033. Ann Transl Med. 2020. PMID: 33313290 Free PMC article. Review.
Congenital cataracts can be associated with other ocular developmental abnormalities, including microphthalmia, microcornea, or aniridia and with systemic findings. Next-generation sequencing (NGS) and forthcoming new ultra-high-throughput sequencing represent excel …
Congenital cataracts can be associated with other ocular developmental abnormalities, including microphthalmia, microcornea, or aniridia and …
Challenges and opportunities for overcoming dog use in agrochemical evaluation and registration.
Bishop PL, Brescia S, Brunner R, Casey W, Conlee-Griffin K, Currie RA, Domoradzki J, Embry M, Harris MI, Hartung T, Hilton GM, Hooberman B, Ingle B, Jang KJ, Kinter L, Krall C, Leedale J, Lowit A, Mehta J, Mendez E, Mingoia B, Munarriz E, Murphy L, Myer A, Ottoni A, Panzarea M, Perron M, Pina J, Ramsingh D, Sewell F, Swanson J, Tan YM, Terron A, Trainer MA, Valadares MC, Webb S, Webb E, Willett C, Wolf DC. Bishop PL, et al. ALTEX. 2023;40(3):534-540. doi: 10.14573/altex.2302151. Epub 2023 Mar 8. ALTEX. 2023. PMID: 36888967 Free article.
Promising novel tools including in vitro comparative metabolism studies, in silico models, and high-throughput assays able to identify metabolites and mechanisms of action leading to development of adverse outcome pathways will need further development. ...
Promising novel tools including in vitro comparative metabolism studies, in silico models, and high-throughput assays able to …
ToxRefDB v2.1: update to curated in vivo study data in the Toxicity Reference Database.
Feshuk M, Kolaczkowski L, Watford S, Paul Friedman K. Feshuk M, et al. Front Toxicol. 2023 Sep 11;5:1260305. doi: 10.3389/ftox.2023.1260305. eCollection 2023. Front Toxicol. 2023. PMID: 37753522 Free PMC article. Review.
The recovered data improves the utility of ToxRefDB as a resource for curated legacy in vivo information, which enhances scientific confidence in vitro high-throughput screening of chemicals and supports retrospective and predictive toxicology applications for which …
The recovered data improves the utility of ToxRefDB as a resource for curated legacy in vivo information, which enhances scientific confiden …
Assessing utility of thyroid in vitro screening assays through comparisons to observed impacts in vivo.
Eytcheson SA, Olker JH, Friedman KP, Hornung MW, Degitz SJ. Eytcheson SA, et al. Regul Toxicol Pharmacol. 2023 Oct;144:105491. doi: 10.1016/j.yrtph.2023.105491. Epub 2023 Sep 4. Regul Toxicol Pharmacol. 2023. PMID: 37666444 Review.
As in vivo testing lacks the throughput to address data gaps on endocrine bioactivity for thousands of chemicals, in vitro high-throughput screening (HTS) methods are being developed to screen larger chemical libraries. ...
As in vivo testing lacks the throughput to address data gaps on endocrine bioactivity for thousands of chemicals, in vitro high-th …
In conversation with Sarah Teichmann.
Dhillon P, Teichmann SA. Dhillon P, et al. FEBS J. 2019 Apr;286(8):1445-1450. doi: 10.1111/febs.14806. FEBS J. 2019. PMID: 31012289 Free article.
20 results