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Showing results for haemin liao
Your search for Haimin Liao retrieved no results
Withaferin A inhibits ferroptosis and protects against intracerebral hemorrhage.
Zhou ZX, Cui Q, Zhang YM, Yang JX, Xiang WJ, Tian N, Jiang YL, Chen ML, Yang B, Li QH, Liao RJ. Zhou ZX, et al. Neural Regen Res. 2023 Jun;18(6):1308-1315. doi: 10.4103/1673-5374.355822. Neural Regen Res. 2023. PMID: 36453416 Free PMC article.
We established a mouse model of ICH by injection of autologous tail artery blood into the caudate nucleus and an in vitro cell model of hemin-induced ICH. WFA was injected intracerebroventricularly at 0.1, 1 or 5 g/kg once daily for 7 days, starting immediately after ICH o …
We established a mouse model of ICH by injection of autologous tail artery blood into the caudate nucleus and an in vitro cell model of h …
A DNA Origami-based Bactericide for Efficient Healing of Infected Wounds.
Wu T, Wang H, Tian R, Guo S, Liao Y, Liu J, Ding B. Wu T, et al. Angew Chem Int Ed Engl. 2023 Nov 13;62(46):e202311698. doi: 10.1002/anie.202311698. Epub 2023 Oct 12. Angew Chem Int Ed Engl. 2023. PMID: 37755438
Herein, we report a DNA origami-based bactericide for efficient anti-infection therapy of infected wounds in vivo. In our design, abundant DNAzymes (G4/hemin) can be precisely organized on the DNA origami for controllable generation of reactive oxygen species (ROS) to brea …
Herein, we report a DNA origami-based bactericide for efficient anti-infection therapy of infected wounds in vivo. In our design, abundant D …
CircLphn3 protects the blood-brain barrier in traumatic brain injury.
Cheng YQ, Wu CR, Du MR, Zhou Q, Wu BY, Fu JY, Balawi E, Tan WL, Liao ZB. Cheng YQ, et al. Neural Regen Res. 2022 Apr;17(4):812-818. doi: 10.4103/1673-5374.322467. Neural Regen Res. 2022. PMID: 34472480 Free PMC article.
We found that the expression of circLphn3 was substantially decreased in mouse models of traumatic brain injury and in hemin-treated bEnd.3 (mouse brain cell line) cells. After overexpressing circLphn3 in bEnd.3 cells, the expression of the tight junction proteins, ZO-1, Z …
We found that the expression of circLphn3 was substantially decreased in mouse models of traumatic brain injury and in hemin-treated …
Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1.
Wang R, Liang Z, Xue X, Mei H, Ji L, Wang B, Chen W, Gao C, Yuan S, Wu T, Qi H, Hu S, Yi L, Song Y, Liao R, Chen B. Wang R, et al. J Cell Mol Med. 2024 Jan;28(1):e18007. doi: 10.1111/jcmm.18007. Epub 2023 Oct 27. J Cell Mol Med. 2024. PMID: 37890842 Free PMC article.
Hemin activated FoxO3a/ATG-mediated autophagy and HO-1 signalling resulting in ferroptosis in vitro and in a mice model of brain haemorrhage. Accordingly, autophagy inhibitor Baf-A1 or HO-1 inhibitor ZnPP protected against hemin-induced ferroptosis. Hemin pro …
Hemin activated FoxO3a/ATG-mediated autophagy and HO-1 signalling resulting in ferroptosis in vitro and in a mice model of brain haem …
Proximity hybridization triggered hybridization chain reaction for label-free electrochemical homogeneous aptasensors.
Liao X, Zhang C, Machuki JO, Wen X, Chen D, Tang Q, Gao F. Liao X, et al. Talanta. 2021 May 1;226:122058. doi: 10.1016/j.talanta.2020.122058. Epub 2021 Jan 14. Talanta. 2021. PMID: 33676642
Thrombin promoted the formation of a complex via the proximity hybridization of the aptamer DNA strands, which unfolded the molecular beacon, the stem part of molecular beacon as a primer to initiate the hybridization chain reaction process. Thus, with the electrochemical indicat …
Thrombin promoted the formation of a complex via the proximity hybridization of the aptamer DNA strands, which unfolded the molecular beacon …
[Structural features and functional mechanism of TonB in some Gram-negative bacteria-A review].
Liao H, Liu M, Cheng A. Liao H, et al. Wei Sheng Wu Xue Bao. 2015 May 4;55(5):529-36. Wei Sheng Wu Xue Bao. 2015. PMID: 26259476 Review. Chinese.
TonB systems consist of plasma membrane proteins ExbB-ExbD and periplasmic protein TonB, which provide the energy to TonB-dependent receptors to transport substrates. These substrates include iron, hemin, vitamin B12, carbohydrate and some transition metal elements. ...
TonB systems consist of plasma membrane proteins ExbB-ExbD and periplasmic protein TonB, which provide the energy to TonB-dependent receptor …
Target-induced activation of DNAzyme for highly sensitive colorimetric detection of bleomycin via DNA scission.
Liao X, Li M, Zou L. Liao X, et al. RSC Adv. 2022 Jun 22;12(29):18296-18300. doi: 10.1039/d2ra02816f. eCollection 2022 Jun 22. RSC Adv. 2022. PMID: 35799941 Free PMC article.
In the presence of BLM, it may cleave the 5'-GT-3' site of the hairpin probe with Fe(ii) as a cofactor, releasing the G-tetrads DNA fragment, which may further bind hemin to form a catalytic G-quadruplex-hemin DNAzyme. The resultant G-quadruplex DNAzyme has notable …
In the presence of BLM, it may cleave the 5'-GT-3' site of the hairpin probe with Fe(ii) as a cofactor, releasing the G-tetrads DNA fragment …
HemU and TonB1 contribute to hemin acquisition in Stenotrophomonas maltophilia.
Liao CH, Lu HF, Yang CW, Yeh TY, Lin YT, Yang TC. Liao CH, et al. Front Cell Infect Microbiol. 2024 Mar 26;14:1380976. doi: 10.3389/fcimb.2024.1380976. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38596648 Free PMC article.
INTRODUCTION: The hemin acquisition system is composed of an outer membrane TonB-dependent transporter that internalizes hemin into the periplasm, periplasmic hemin-binding proteins to shuttle hemin, an inner membrane transporter that transports hem …
INTRODUCTION: The hemin acquisition system is composed of an outer membrane TonB-dependent transporter that internalizes hemin …
Label-free fluorescent and electrochemical biosensors based on defective G-quadruplexes.
Zhang J, Wang LL, Hou MF, Luo LP, Liao YJ, Xia YK, Yan A, Weng YP, Zeng LP, Chen JH. Zhang J, et al. Biosens Bioelectron. 2018 Oct 30;118:1-8. doi: 10.1016/j.bios.2018.07.033. Epub 2018 Jul 18. Biosens Bioelectron. 2018. PMID: 30041159
Accordingly, ThT or hemin can selectively combine with G-quadruplex, giving rise to distinct fluorescent or current signal changes for label-free detection of guanine. Benefiting from the perfect discriminative ability of guanine towards DGQ and ThT/hemin against st …
Accordingly, ThT or hemin can selectively combine with G-quadruplex, giving rise to distinct fluorescent or current signal changes fo …
DNAzyme-driven bipedal DNA walker for label-free and signal-on electrochemical detection of amyloid-β oligomer.
Wei J, Ge K, Gong Y, Li L, Tang Q, Liao X, Zhang G, Gao F. Wei J, et al. Int J Biol Macromol. 2023 Feb 15;228:234-241. doi: 10.1016/j.ijbiomac.2022.12.216. Epub 2022 Dec 22. Int J Biol Macromol. 2023. PMID: 36566812
The DNAwalker is powered by an Mg(2+)-dependent DNAzyme, and the binding-induced DNAwalker continuously clamps the MB, unlocking several active G-quadruplex-forming sequences. These G-quadruplexes can be further combined by hemin to generate a G-quadruplex/heme complex, re …
The DNAwalker is powered by an Mg(2+)-dependent DNAzyme, and the binding-induced DNAwalker continuously clamps the MB, unlocking several act …
38 results