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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1982 2
1987 2
1988 1
1989 2
1992 2
1993 1
1994 1
1995 3
1996 4
1997 3
1998 1
1999 4
2000 5
2001 6
2002 4
2003 9
2004 13
2005 5
2006 12
2007 12
2008 25
2009 33
2010 27
2011 37
2012 29
2013 32
2014 58
2015 80
2016 88
2017 99
2018 105
2019 132
2020 105
2021 152
2022 156
2023 147
2024 63

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1,254 results

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Page 1
Methylphenidate.
Verghese C, Abdijadid S. Verghese C, et al. 2023 Jan 2. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jan 2. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29494058 Free Books & Documents.
Off-label uses of methylphenidate include treatment for fatigue in patients with cancer, refractory depression in the geriatric population, apathy in Alzheimer's disease, and enhancing cognitive performance (e.g., memory). The efficacy of methylphenidate for its off-label …
Off-label uses of methylphenidate include treatment for fatigue in patients with cancer, refractory depression in the geriatric population, …
Naphthalene Diimides as Multimodal G-Quadruplex-Selective Ligands.
Pirota V, Nadai M, Doria F, Richter SN. Pirota V, et al. Molecules. 2019 Jan 24;24(3):426. doi: 10.3390/molecules24030426. Molecules. 2019. PMID: 30682828 Free PMC article. Review.
G-quadruplexes are four-stranded nucleic acids structures that can form in guanine-rich sequences. ...We present the latest developments on naphthalene diimides as G-quadruplex ligands, focusing on their ability to bind G-quadruplexes at telomeres and oncogen …
G-quadruplexes are four-stranded nucleic acids structures that can form in guanine-rich sequences. ...We present the latest developme …
Oxazepam.
Singh R, Abdijadid S. Singh R, et al. 2023 May 22. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 May 22. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 31335069 Free Books & Documents.
This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for members of the interprofessional team in the management of …
This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pha …
Targeting G-quadruplexes to achieve antiviral activity.
Ruggiero E, Richter SN. Ruggiero E, et al. Bioorg Med Chem Lett. 2023 Jan 1;79:129085. doi: 10.1016/j.bmcl.2022.129085. Epub 2022 Nov 21. Bioorg Med Chem Lett. 2023. PMID: 36423824 Free PMC article. Review.
Recently, nucleic acids have been shown to fold in structures alternative to the classic double helix and Watson and Crick base-pairing. Among these non-canonical structures, G-quadruplexes (G4s) have attracted interest because of their key biological roles that are being …
Recently, nucleic acids have been shown to fold in structures alternative to the classic double helix and Watson and Crick base-pairing. Amo …
Multimeric G-quadruplexes: A review on their biological roles and targeting.
Frasson I, Pirota V, Richter SN, Doria F. Frasson I, et al. Int J Biol Macromol. 2022 Apr 15;204:89-102. doi: 10.1016/j.ijbiomac.2022.01.197. Epub 2022 Feb 4. Int J Biol Macromol. 2022. PMID: 35124022 Free article. Review.
In human cells, nucleic acids adopt several non-canonical structures that regulate key cellular processes. Among them, G-quadruplexes (G4s) are stable structures that form in guanine-rich regions in vitro and in cells. ...
In human cells, nucleic acids adopt several non-canonical structures that regulate key cellular processes. Among them, G-quadruplexes …
Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer's disease.
Calafate S, Özturan G, Thrupp N, Vanderlinden J, Santa-Marinha L, Morais-Ribeiro R, Ruggiero A, Bozic I, Rusterholz T, Lorente-Echeverría B, Dias M, Chen WT, Fiers M, Lu A, Vlaeminck I, Creemers E, Craessaerts K, Vandenbempt J, van Boekholdt L, Poovathingal S, Davie K, Thal DR, Wierda K, Oliveira TG, Slutsky I, Adamantidis A, De Strooper B, de Wit J. Calafate S, et al. Nat Neurosci. 2023 Jun;26(6):1021-1031. doi: 10.1038/s41593-023-01325-4. Epub 2023 May 15. Nat Neurosci. 2023. PMID: 37188873 Free PMC article.
We show that MCH downregulates synaptic transmission, modulates firing rate homeostasis in hippocampal neurons and reverses the increased excitatory drive to CA1 neurons in App(NL-G-F) mice. App(NL-G-F) mice spend less time in rapid eye movement (REM) sleep. App(NL- …
We show that MCH downregulates synaptic transmission, modulates firing rate homeostasis in hippocampal neurons and reverses the increased ex …
Trial of N-Acetyl-l-Leucine in Niemann-Pick Disease Type C.
Bremova-Ertl T, Ramaswami U, Brands M, Foltan T, Gautschi M, Gissen P, Gowing F, Hahn A, Jones S, Kay R, Kolnikova M, Arash-Kaps L, Marquardt T, Mengel E, Park JH, Reichmannová S, Schneider SA, Sivananthan S, Walterfang M, Wibawa P, Strupp M, Martakis K. Bremova-Ertl T, et al. N Engl J Med. 2024 Feb 1;390(5):421-431. doi: 10.1056/NEJMoa2310151. N Engl J Med. 2024. PMID: 38294974 Clinical Trial.
NALL or matching placebo was administered orally two to three times per day, with patients 4 to 12 years of age receiving weight-based doses (2 to 4 g per day) and those 13 years of age or older receiving a dose of 4 g per day. The primary end point was the total sc …
NALL or matching placebo was administered orally two to three times per day, with patients 4 to 12 years of age receiving weight-based doses …
Radiocapitellar plica: a narrative review.
Colozza A, Martini I, Cavaciocchi M, Menozzi M, Padovani S, Belluati A. Colozza A, et al. Acta Biomed. 2022 Mar 14;93(1):e2022029. doi: 10.23750/abm.v93i1.10950. Acta Biomed. 2022. PMID: 35315424 Free PMC article. Review.
Suspension torture and its physical sequelae.
Woldu S, Brasholt M. Woldu S, et al. J Forensic Leg Med. 2021 May;80:102155. doi: 10.1016/j.jflm.2021.102155. Epub 2021 Apr 1. J Forensic Leg Med. 2021. PMID: 33836478 Review.
The review includes the prevalence, geographical distribution and description of variations of suspension torture. Physical sequelae like nerve injuries, e.g. brachial plexus injuries, scars, joint dislocation and possible causes of death will be described in detail. ...
The review includes the prevalence, geographical distribution and description of variations of suspension torture. Physical sequelae like ne …
Autoimmune pancreatitis: Cornerstones and future perspectives.
Gallo C, Dispinzieri G, Zucchini N, Invernizzi P, Massironi S. Gallo C, et al. World J Gastroenterol. 2024 Feb 28;30(8):817-832. doi: 10.3748/wjg.v30.i8.817. World J Gastroenterol. 2024. PMID: 38516247 Free PMC article. Review.
1,254 results