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Serum β2-microglobulin levels in Coronavirus disease 2019 (Covid-19): Another prognosticator of disease severity?
Conca W, Alabdely M, Albaiz F, Foster MW, Alamri M, Alkaff M, Al-Mohanna F, Nagelkerke N, Almaghrabi RS. Conca W, et al. PLoS One. 2021 Mar 1;16(3):e0247758. doi: 10.1371/journal.pone.0247758. eCollection 2021. PLoS One. 2021. PMID: 33647017 Free PMC article.
Shed beta2-m is measurable in circulation, and various disorders are accompanied by increases in beta2-m levels, including several viral infections. ...In multivariate ordinal regression beta2-m levels were the only significant predictor of disease severity. …
Shed beta2-m is measurable in circulation, and various disorders are accompanied by increases in beta2-m levels, including sev …
Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression.
Al-Anazi A, Parhar R, Saleh S, Al-Hijailan R, Inglis A, Al-Jufan M, Bazzi M, Hashmi S, Conca W, Collison K, Al-Mohanna F. Al-Anazi A, et al. Data Brief. 2018 Nov 1;21:2395-2397. doi: 10.1016/j.dib.2018.10.147. eCollection 2018 Dec. Data Brief. 2018. PMID: 30547064 Free PMC article.
Data illustrate hypoxia-induced VEGF and leptin expression in human adipocytes treated with the calcium chelator BAPTA-AM (1 M). It also shows NF-kappaB p65 induced expression by hypoxia. ...
Data illustrate hypoxia-induced VEGF and leptin expression in human adipocytes treated with the calcium chelator BAPTA-AM (1 M). It a …
A null mutation in MICU2 causes abnormal mitochondrial calcium homeostasis and a severe neurodevelopmental disorder.
Shamseldin HE, Alasmari A, Salih MA, Samman MM, Mian SA, Alshidi T, Ibrahim N, Hashem M, Faqeih E, Al-Mohanna F, Alkuraya FS. Shamseldin HE, et al. Brain. 2017 Nov 1;140(11):2806-2813. doi: 10.1093/brain/awx237. Brain. 2017. PMID: 29053821
MICU2 is a major component of the mitochondrial calcium uniporter complex and its deficiency has been shown to impair mitochondrial calcium [Ca2+]m homeostasis although the exact mechanism remains unclear. We used exome sequencing, positional mapping, and functional charac …
MICU2 is a major component of the mitochondrial calcium uniporter complex and its deficiency has been shown to impair mitochondrial calcium …
An atypical pulmonary fibrosis is associated with co-inheritance of mutations in the calcium binding protein genes S100A3 and S100A13.
Al-Mutairy EA, Imtiaz FA, Khalid M, Al Qattan S, Saleh S, Mahmoud LM, Al-Saif MM, Al-Haj L, Al-Enazi A, AlJebreen AM, Mohammed SF, Mobeireek AF, Alkattan K, Chisti MA, Luzina IG, Al-Owain M, Weheba I, Abdelsayed AM, Ramzan K, Janssen LJ, Conca W, Alaiya A, Collison KS, Meyer BF, Atamas SP, Khabar KS, Hasday JD, Al-Mohanna F. Al-Mutairy EA, et al. Eur Respir J. 2019 Jul 18;54(1):1802041. doi: 10.1183/13993003.02041-2018. Print 2019 Jul. Eur Respir J. 2019. PMID: 31073086 Free PMC article.
Ribonucleic acid interference targeting S100A4 (Mts1) suppresses tumor growth and metastasis of anaplastic thyroid carcinoma in a mouse model.
Shi Y, Zou M, Collison K, Baitei EY, Al-Makhalafi Z, Farid NR, Al-Mohanna FA. Shi Y, et al. J Clin Endocrinol Metab. 2006 Jun;91(6):2373-9. doi: 10.1210/jc.2006-0155. Epub 2006 Mar 21. J Clin Endocrinol Metab. 2006. PMID: 16551737
The growth rate of ARO/S100A4-shRNA was reduced by 46 +/- 7.6% in a cell proliferation assay. Cell cycle analysis showed increased G(2)/M accumulation in ARO/S100A4-shRNA. Tumor formation and growth induced by sc injection of 5 x 10(6) ARO/S100A4-shRNA into the nude mice w …
The growth rate of ARO/S100A4-shRNA was reduced by 46 +/- 7.6% in a cell proliferation assay. Cell cycle analysis showed increased G(2)/M …