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Turmeronols (A and B) from Curcuma longa have anti-inflammatory effects in lipopolysaccharide-stimulated BV-2 microglial cells by reducing NF-κB signaling.
Saji R, Uchio R, Fuwa A, Okuda-Hanafusa C, Kawasaki K, Muroyama K, Murosaki S, Yamamoto Y, Hirose Y. Saji R, et al. Among authors: okuda hanafusa c. Biosci Microbiota Food Health. 2023;42(3):172-179. doi: 10.12938/bmfh.2022-071. Epub 2023 Jan 27. Biosci Microbiota Food Health. 2023. PMID: 37404570 Free PMC article.
A Hot Water Extract of Curcuma longa L. Improves Fasting Serum Glucose Levels in Participants with Low-Grade Inflammation: Reanalysis of Data from Two Randomized, Double-Blind, Placebo-Controlled Trials.
Uchio R, Okuda-Hanafusa C, Saji R, Kawasaki K, Muroyama K, Murosaki S, Yamamoto Y, Hirose Y. Uchio R, et al. Among authors: okuda hanafusa c. Nutrients. 2022 Sep 13;14(18):3763. doi: 10.3390/nu14183763. Nutrients. 2022. PMID: 36145139 Free PMC article. Clinical Trial.
Inhibitory effect of the compounds from the water extract of Curcuma longa on the production of PGE2 and NO in a macrophage cell line stimulated by LPS.
Kawasaki K, Okuda-Hanafusa C, Aoyagi M, Taoka K, Yamamoto N, Muroyama K, Murosaki S, Yamamoto Y. Kawasaki K, et al. Among authors: okuda hanafusa c. Biosci Biotechnol Biochem. 2018 Dec;82(12):2109-2117. doi: 10.1080/09168451.2018.1511366. Epub 2018 Aug 26. Biosci Biotechnol Biochem. 2018. PMID: 30146952
Curcuma longa extract reduces serum inflammatory markers and postprandial hyperglycemia in healthy but borderline participants with overweight and glycemia in the normal/prediabetes range: a randomized, double-blind, and placebo-controlled trial.
Uchio R, Okuda-Hanafusa C, Sakaguchi H, Saji R, Muroyama K, Murosaki S, Yamamoto Y, Hirose Y. Uchio R, et al. Among authors: okuda hanafusa c. Front Nutr. 2024 Jan 29;11:1324196. doi: 10.3389/fnut.2024.1324196. eCollection 2024. Front Nutr. 2024. PMID: 38347961 Free PMC article.
Hot Water Extract of Curcuma longa L. Improves Serum Inflammatory Markers and General Health in Subjects with Overweight or Prehypertension/Mild Hypertension: A Randomized, Double-Blind, Placebo-Controlled Trial.
Uchio R, Muroyama K, Okuda-Hanafusa C, Kawasaki K, Yamamoto Y, Murosaki S. Uchio R, et al. Among authors: okuda hanafusa c. Nutrients. 2019 Aug 7;11(8):1822. doi: 10.3390/nu11081822. Nutrients. 2019. PMID: 31394768 Free PMC article. Clinical Trial.