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Page 1
7-p-Tolyl-10,11-dihydro-benzo[h]furo[3,4-b]quinolin-8(7H)-one.
Shi C. Shi C. Acta Crystallogr Sect E Struct Rep Online. 2010 Feb 20;66(Pt 3):o668. doi: 10.1107/S160053681000591X. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21580416 Free PMC article.
In the title compound, C(22)H(17)NO(2), the fused ring system is essentially planar (r.m.s. deviation = 0.021 A) and the dihedral angle between the dihydro-pyridine and tolyl rings is 80.98 (11). In the crystal, the mol-ecules are linked into chains along the b axis …
In the title compound, C(22)H(17)NO(2), the fused ring system is essentially planar (r.m.s. deviation = 0.021 A) and the dihedral ang …
Opipramol.
Fun HK, Loh WS, Siddegowda MS, Yathirajan HS, Narayana B. Fun HK, et al. Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1598. doi: 10.1107/S1600536811021131. Epub 2011 Jun 11. Acta Crystallogr Sect E Struct Rep Online. 2011. PMID: 21837006 Free PMC article.
2-{4-[3-(5H-dibenz[b,f]azepin-5-yl)prop-yl]piperazin-1-yl}ethanol), C(23)H(29)N(3)O, the 5H-dibenz[b,f]azepine and piperazine rings adopt boat and chair conformations, respectively, and the overall shape of the fused ring part of the molecule is a butterfly. …
2-{4-[3-(5H-dibenz[b,f]azepin-5-yl)prop-yl]piperazin-1-yl}ethanol), C(23)H(29)N(3)O, the 5H-dibenz[b,f]azepine and pipe …
6-Methyl-ideneandrost-4-ene-3,17-dione.
Andrade LC, de Almeida MJ, Fernandes Roleira FM, Varela CL, Tavares da Silva EJ. Andrade LC, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 Apr 1;68(Pt 4):o1263. doi: 10.1107/S1600536812013207. Epub 2012 Mar 31. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22606192 Free PMC article.
In the title compound, C(20)H(26)O(2), which is the 6-methyl-ene derivative of androstenedione and a synthetic percursor of exemestane, the steroid A ring approximates to a sofa (or envelope) conformation, with the methyl-ene group adjacent to the link to the B ring …
In the title compound, C(20)H(26)O(2), which is the 6-methyl-ene derivative of androstenedione and a synthetic percursor of exemestan …
Efficient neutron capture therapy of glioblastoma with pteroyl-closo-dodecaborate-conjugated 4-(p-iodophenyl)butyric acid (PBC-IP).
Nishimura K, Kashiwagi H, Morita T, Fukuo Y, Okada S, Miura K, Matsumoto Y, Sugawara Y, Enomoto T, Suzuki M, Nakai K, Kawabata S, Nakamura H. Nishimura K, et al. J Control Release. 2023 Aug;360:249-259. doi: 10.1016/j.jconrel.2023.06.022. Epub 2023 Jun 29. J Control Release. 2023. PMID: 37356755
PBC-IP administrated intravenously to the human glioblastoma (U87MG) xenograft model showed higher boron accumulation in tumors (29.8 mug [(10)B]/g at 6 h) than BPA (9.6 mug [(10)B]/g at 3 h) at a 25 mg [(10)B]/kg dose, effectively suppressing t …
PBC-IP administrated intravenously to the human glioblastoma (U87MG) xenograft model showed higher boron accumulation in tumors (29.8 mug [( …
Studies of Lewis antigens and H. pylori adhesion in CHO cell lines engineered to express Lewis b determinants.
Löfling J, Diswall M, Eriksson S, Borén T, Breimer ME, Holgersson J. Löfling J, et al. Glycobiology. 2008 Jul;18(7):494-501. doi: 10.1093/glycob/cwn030. Epub 2008 Apr 9. Glycobiology. 2008. PMID: 18400963
Both clones, as well as the parental CHO-K1 cells, expressed Le(x) on GLs. A Le(b)-binding H. pylori strain bound to the 1C5 and 2C2 cells. ...Both clones examined supported adhesion of a Le(b)-binding H. pylori strain and may thus be a useful i …
Both clones, as well as the parental CHO-K1 cells, expressed Le(x) on GLs. A Le(b)-binding H. pylori strain bound to th …
Swietenolide monohydrate.
Tan SK, Osman H, Wong KC, Fun HK, Chantrapromma S. Tan SK, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Jun 13;64(Pt 7):o1267-8. doi: 10.1107/S1600536808017431. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21202901 Free PMC article.
The title compound, a natural b,d-seco-limonoid, C(27)H(34)O(8).H(2)O, and known as Swietenolide monohydrate, has been isolated from S. macrophylla King. In the molecular structure, the four fused six-membered rings adopt twist-boat (ring A), approximate chai …
The title compound, a natural b,d-seco-limonoid, C(27)H(34)O(8).H(2)O, and known as Swietenolide monohydrate, has been …
COR758, a negative allosteric modulator of GABA(B) receptors.
Porcu A, Mostallino R, Serra V, Melis M, Sogos V, Beggiato S, Ferraro L, Manetti F, Gianibbi B, Bettler B, Corelli F, Mugnaini C, Castelli MP. Porcu A, et al. Neuropharmacology. 2021 May 15;189:108537. doi: 10.1016/j.neuropharm.2021.108537. Epub 2021 Mar 30. Neuropharmacology. 2021. PMID: 33798546
In the present study, we report the characterization of COR758, which acts as GABA(B)R NAM in rat cortical membranes and CHO cells stably expressing GABA(B)Rs (CHO-GABA(B)). ...Bioluminescent resonance energy transfer (BRET) measurements in C …
In the present study, we report the characterization of COR758, which acts as GABA(B)R NAM in rat cortical membranes and CHO c …
Creatininium 2-chloro-acetate.
Ali AJ, Athimoolam S, Bahadur SA. Ali AJ, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 May 1;68(Pt 5):o1285-6. doi: 10.1107/S1600536812012068. Epub 2012 Apr 4. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22590198 Free PMC article.
2-amino-1-methyl-4-oxo-4,5-dihydro-1H-imidazol-3-ium 2-chloro-acetate), C(4)H(8)N(3)O(+).C(2)H(2)ClO(2) (-), the mol-ecular aggregations are stabil-ized through classical (N-HO) and non-classical (C-HO and C-HN) hydrogen-bonding inter-actions. ...Further weak C-HN i …
2-amino-1-methyl-4-oxo-4,5-dihydro-1H-imidazol-3-ium 2-chloro-acetate), C(4)H(8)N(3)O(+).C(2)H(2)ClO(2) (-), the mol-ecular ag …
7,199 results