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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 1
2006 2
2008 2
2010 1
2014 1
2015 2
2016 3
2017 6
2018 1
2019 1
2020 2
2021 6
2022 1
2023 2
2024 4

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34 results

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Page 1
Discovery of Nanomolar DCAF1 Small Molecule Ligands.
Li ASM, Kimani S, Wilson B, Noureldin M, González-Álvarez H, Mamai A, Hoffer L, Guilinger JP, Zhang Y, von Rechenberg M, Disch JS, Mulhern CJ, Slakman BL, Cuozzo JW, Dong A, Poda G, Mohammed M, Saraon P, Mittal M, Modh P, Rathod V, Patel B, Ackloo S, Santhakumar V, Szewczyk MM, Barsyte-Lovejoy D, Arrowsmith CH, Marcellus R, Guié MA, Keefe AD, Brown PJ, Halabelian L, Al-Awar R, Vedadi M. Li ASM, et al. Among authors: keefe ad. J Med Chem. 2023 Apr 13;66(7):5041-5060. doi: 10.1021/acs.jmedchem.2c02132. Epub 2023 Mar 22. J Med Chem. 2023. PMID: 36948210 Free PMC article.
Aptamers as therapeutics.
Keefe AD, Pai S, Ellington A. Keefe AD, et al. Nat Rev Drug Discov. 2010 Jul;9(7):537-50. doi: 10.1038/nrd3141. Nat Rev Drug Discov. 2010. PMID: 20592747 Free PMC article. Review.
SELEX with modified nucleotides.
Keefe AD, Cload ST. Keefe AD, et al. Curr Opin Chem Biol. 2008 Aug;12(4):448-56. doi: 10.1016/j.cbpa.2008.06.028. Epub 2008 Jul 21. Curr Opin Chem Biol. 2008. PMID: 18644461 Review.
Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning.
Ahmad S, Xu J, Feng JA, Hutchinson A, Zeng H, Ghiabi P, Dong A, Centrella PA, Clark MA, Guié MA, Guilinger JP, Keefe AD, Zhang Y, Cerruti T, Cuozzo JW, von Rechenberg M, Bolotokova A, Li Y, Loppnau P, Seitova A, Li YY, Santhakumar V, Brown PJ, Ackloo S, Halabelian L. Ahmad S, et al. Among authors: keefe ad. J Med Chem. 2023 Dec 14;66(23):16051-16061. doi: 10.1021/acs.jmedchem.3c01471. Epub 2023 Nov 23. J Med Chem. 2023. PMID: 37996079
34 results