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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
2008 2
2009 2
2010 7
2011 7
2012 4
2013 4
2014 6
2015 3
2016 2
2017 6
2018 8
2019 6
2020 18
2021 10
2022 12
2023 17
2024 4

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102 results

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Page 1
Proteolysis-targeting chimeras with reduced off-targets.
Nguyen TM, Sreekanth V, Deb A, Kokkonda P, Tiwari PK, Donovan KA, Shoba V, Chaudhary SK, Mercer JAM, Lai S, Sadagopan A, Jan M, Fischer ES, Liu DR, Ebert BL, Choudhary A. Nguyen TM, et al. Among authors: choudhary a. Nat Chem. 2024 Feb;16(2):218-228. doi: 10.1038/s41557-023-01379-8. Epub 2023 Dec 18. Nat Chem. 2024. PMID: 38110475 Free PMC article.
Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways.
Basile G, Vetere A, Hu J, Ijaduola O, Zhang Y, Liu KC, Eltony AM, De Jesus DF, Fukuda K, Doherty G, Leech CA, Chepurny OG, Holz GG, Yun SH, Andersson O, Choudhary A, Wagner BK, Kulkarni RN. Basile G, et al. Among authors: choudhary a. Cell Metab. 2023 Jul 11;35(7):1242-1260.e9. doi: 10.1016/j.cmet.2023.05.007. Epub 2023 Jun 19. Cell Metab. 2023. PMID: 37339634 Free PMC article.
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.
Wieder N, Fried JC, Kim C, Sidhom EH, Brown MR, Marshall JL, Arevalo C, Dvela-Levitt M, Kost-Alimova M, Sieber J, Gabriel KR, Pacheco J, Clish C, Abbasi HS, Singh S, Rutter JC, Therrien M, Yoon H, Lai ZW, Baublis A, Subramanian R, Devkota R, Small J, Sreekanth V, Han M, Lim D, Carpenter AE, Flannick J, Finucane H, Haigis MC, Claussnitzer M, Sheu E, Stevens B, Wagner BK, Choudhary A, Shaw JL, Pablo JL, Greka A. Wieder N, et al. Among authors: choudhary a. Cell Metab. 2023 May 2;35(5):887-905.e11. doi: 10.1016/j.cmet.2023.03.018. Epub 2023 Apr 18. Cell Metab. 2023. PMID: 37075753 Free PMC article.
Genome Editing: The Future Begins!
Choudhary A, Goodman C. Choudhary A, et al. Biochemistry. 2023 Dec 19;62(24):3453-3454. doi: 10.1021/acs.biochem.3c00671. Biochemistry. 2023. PMID: 38111351 No abstract available.
A molecular glue approach to control the half-life of CRISPR-based technologies.
Sreekanth V, Jan M, Zhao KT, Lim D, Davis JR, McConkey M, Kovalcik V, Barkal S, Law BK, Fife J, Tian R, Vinyard ME, Becerra B, Kampmann M, Sherwood RI, Pinello L, Liu DR, Ebert BL, Choudhary A. Sreekanth V, et al. Among authors: choudhary a. bioRxiv [Preprint]. 2023 Mar 20:2023.03.12.531757. doi: 10.1101/2023.03.12.531757. bioRxiv. 2023. PMID: 36945568 Free PMC article. Preprint.
Bifunctional modalities for repurposing protein function.
Modell AE, Lai S, Nguyen TM, Choudhary A. Modell AE, et al. Among authors: choudhary a. Cell Chem Biol. 2021 Jul 15;28(7):1081-1089. doi: 10.1016/j.chembiol.2021.06.005. Cell Chem Biol. 2021. PMID: 34270935 Free article. Review.
CRISPR-based therapeutics: current challenges and future applications.
Modell AE, Lim D, Nguyen TM, Sreekanth V, Choudhary A. Modell AE, et al. Among authors: choudhary a. Trends Pharmacol Sci. 2022 Feb;43(2):151-161. doi: 10.1016/j.tips.2021.10.012. Epub 2021 Dec 21. Trends Pharmacol Sci. 2022. PMID: 34952739 Free PMC article. Review.
Chemical and optical control of CRISPR-associated nucleases.
Modell AE, Siriwardena SU, Shoba VM, Li X, Choudhary A. Modell AE, et al. Among authors: choudhary a. Curr Opin Chem Biol. 2021 Feb;60:113-121. doi: 10.1016/j.cbpa.2020.10.003. Epub 2020 Nov 27. Curr Opin Chem Biol. 2021. PMID: 33253976 Review.
Proximity-inducing modalities: the past, present, and future.
Singh S, Tian W, Severance ZC, Chaudhary SK, Anokhina V, Mondal B, Pergu R, Singh P, Dhawa U, Singha S, Choudhary A. Singh S, et al. Among authors: choudhary a. Chem Soc Rev. 2023 Aug 14;52(16):5485-5515. doi: 10.1039/d2cs00943a. Chem Soc Rev. 2023. PMID: 37477631 Review.
102 results